There are substantial limitations in our understanding of the distribution of antimicrobial resistance (AMR) in humans and livestock in developing countries. Here, we present the results of an epidemiological study examining patterns of AMR in Escherichia coli isolates circulating in sympatric hu...
Muloi, Dishon
,
Kiiru, J.
,
Ward, M.J.
,
Hassell, James M.
,
Bettridge, Judy M.
,
Robinson, T.P.
,
Bunnik, B.A.D. van
,
Chase-Topping, M.
,
Robertson, G.
,
Pedersen, A.B.
,
Fèvre, Eric M.
,
Woolhouse, Mark E.J.
,
Kang'ethe, Erastus K.
,
Kariuki, S.
,
[Epidemiology of antimicrobial-resistant Escherichia coli carriage in sympatric humans and livestock in a rapidly urbanizing city]
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Epidemiology of antimicrobial-resistant Escherichia coli carriage in sympatric humans and livestock in a rapidly urbanizing city
Background
Antimicrobial resistance (AMR) driven by antibiotic consumption is a growing global health threat. However, data on antimicrobial consumption patterns in low- and middle-income countries (LMICs) is sparse. Here, we investigate the patterns of antibiotic sales in humans and livestock in...
Muloi, Dishon
,
Fèvre, Eric M.
,
Bettridge, Judy M.
,
Rono, Robert
,
Ong’are, Daniel
,
Hassell, James M.
,
Karani, Maurice K.
,
Muinde, Patrick
,
Bunnik, B. van
,
Street, A.
,
Chase-Topping, M.
,
Pedersen, A.B.
,
Ward, M.J.
,
Woolhouse, Mark E.J.
,
[A cross-sectional survey of practices and knowledge among antibiotic retailers in Nairobi, Kenya]
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A cross-sectional survey of practices and knowledge among antibiotic retailers in Nairobi, Kenya
Surveillance of diseases in Kenya and elsewhere in East Africa is currently carried out by both human and animal health sectors. However, a recent evaluation highlighted the lack of integration between these sectors, leading to disease under-reporting and inefficiencies. This project aimed to dev...
Falzon, Laura C.
,
Alumasa, Lorren
,
Amanya, Fredrick
,
Kang'ethe, Erastus K.
,
Kariuki, Samuel
,
Momanyi, Kelvin
,
Muinde, Patrick
,
Murungi, Maurice K.
,
Njoroge, Samuel M.
,
Ogendo, Allan
,
Ogola, Joseph
,
Rushton, Jonathan
,
Woolhouse, Mark E.J.
,
Fèvre, Eric M.
,
[One Health in action: Operational aspects of an integrated surveillance system for zoonoses in western Kenya]
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One Health in action: Operational aspects of an integrated surveillance system for zoonoses in western Kenya
Fèvre, Eric M.
,
Woolhouse, Mark E.J.
,
Davila, J.
,
Grace, Delia
,
Kang'ethe, Erastus K.
,
Kariuki, S.
,
Kyobutungi, C.
,
Robinson, Timothy P.
,
Rushton, Jonathan
,
Tacoli, C.
,
[Epidemiology, ecology and socio-economics of disease emergence in Nairobi]
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Epidemiology, ecology and socio-economics of disease emergence in Nairobi
Background
Antimicrobial resistance is one of the great challenges facing global health security in the modern era. Wildlife, particularly those that use urban environments, are an important but understudied component of epidemiology of antimicrobial resistance. We investigated antimicrobial resi...
Hassell, J.M.
,
Ward, M.J.
,
Muloi, D.
,
Bettridge, Judy M.
,
Robinson, T.P.
,
Kariuki, S.
,
Ogendo, A.
,
Kiiru, J.
,
Imboma, T.
,
Kang'ethe, Erastus K.
,
Öghren, E.M.
,
Williams, N.J.
,
Begon, M.
,
Woolhouse, Mark E.J.
,
Fèvre, Eric M.
,
[Clinically relevant antimicrobial resistance at the wildlife–livestock–human interface in Nairobi: An epidemiological study]
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Clinically relevant antimicrobial resistance at the wildlife–livestock–human interface in Nairobi: An epidemiological study
Land-use change is predicted to act as a driver of zoonotic disease emergence through human exposure to novel microbial diversity, but evidence for the effects of environmental change on microbial communities in vertebrates is lacking. We sample wild birds at 99 wildlife-livestock-human interface...
Hassell, J.M.
,
Ward, M.J.
,
Muloi, D.
,
Bettridge, Judy M.
,
Phan, H.
,
Robinson, T.P.
,
Ogendo, A.
,
Imboma, T.
,
Kiiru, J.
,
Kariuki, S.
,
Begon, M.
,
Kang'ethe, Erastus K.
,
Woolhouse, Mark E.J.
,
Fèvre, Eric M.
,
[Deterministic processes structure bacterial genetic communities across an urban landscape]
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Deterministic processes structure bacterial genetic communities across an urban landscape
Robinson, Timothy P.
,
Bu, D.P.
,
Carrique-Mas, J.
,
Fèvre, Eric M.
,
Gilbert, M.
,
Grace, Delia
,
Hay, S.I.
,
Jiwakanon, J.
,
Kakkar, M.
,
Kariuki, S.
,
Laxminarayan, R.
,
Lubroth, J.
,
Magnusson, Ulf
,
Thi Ngoc, P.
,
Boeckel, Thomas P. van
,
Woolhouse, Mark E.J.
,
[Antibiotic resistance is the quintessential One Health issue]
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Antibiotic resistance is the quintessential One Health issue
Robinson, Timothy P.
,
Bu, D.P.
,
Carrique-Mas, J.
,
Fèvre, Eric M.
,
Gilbert, M.
,
Grace, Delia
,
Hay, S.I.
,
Jiwakanon, J.
,
Kakkar, M.
,
Kariuki, S.
,
Laxminarayan, R.
,
Lubroth, J.
,
Magnusson, Ulf
,
Thi Ngoc, P.
,
Boeckel, Thomas P. van
,
Woolhouse, Mark E.J.
,
[Antibiotic resistance: mitigation opportunities in livestock sector development]
,
Antibiotic resistance: mitigation opportunities in livestock sector development
The role of farm animals in the emergence and dissemination of both AMR bacteria and their resistance determinants to humans is poorly understood and controversial. Here, we systematically reviewed the current evidence that food animals are responsible for transfer of AMR to humans. We searched P...
Muloi, D.
,
Ward, M.J.
,
Pedersen, A.B.
,
Fèvre, Eric M.
,
Woolhouse, Mark E.J.
,
Bunnik, B.A.D. van
,
[Are food animals responsible for transfer of antimicrobial-resistant Escherichia coli or their resistance determinants to human populations? A systematic review]
,
Are food animals responsible for transfer of antimicrobial-resistant Escherichia coli or their resistance determinants to human populations? A systematic review