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A1899 is a potent and a highly selective blocker of the two-­pore domain potassium (K2P) channel TASK-­1. It acts as an antagonist blocking the K+ flux and binds to TASK-­1 in the inner cavity, showing activity in the nanomolar order. A1899 travels throug


The acidithiobacilli are sulfur-oxidizing acidophilic bacteria that thrive in both natural and anthropogenic low pH environments. They contribute to processes that lead to the generation of acid rock drainage in several different geoclimatic contexts, and


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