Salp15, a 15-kDa tick salivary gland protein, has several suppressive modes of activity against host immunity and plays a critical role in the transmission of Lyme disease spirochetes in Ixodes scapularis and Ixodes ricinus, major vectors of Lyme disease in North America and Western Europe. Salp1...
Murase, Y.
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Konnai, S.
,
Yamada, S.
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Githaka, Naftaly W.
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Isezaki, M.
,
Ito, T.
,
Takano, A.
,
Ando, S.
,
Kawabata, H.
,
Murata, S.
,
Ohashi, K.
,
[An investigation of binding ability of Ixodes persulcatus Schulze Salp15 with Lyme disease spirochetes]
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An investigation of binding ability of Ixodes persulcatus Schulze Salp15 with Lyme disease spirochetes
Ixodes ricinus immunosuppressor (Iris) is a tick salivary gland protein derived from I. ricinus. In this study, Iris homolog was identified in the salivary glands of Ixodes persulcatus, which is the specific vector of the Lyme disease agent in Japan. The homolog was named Ipis-1. To investigate t...
Toyomane, K.
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Konnai, S.
,
Niwa, A.
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Githaka, Naftaly W.
,
Isezaki, M.
,
Yamada, S.
,
Ito, T.
,
Takano, A.
,
Ando, S.
,
Kawabata, H.
,
Murata, S.
,
Ohashi, K.
,
[Identification and the preliminary in vitro characterization of IRIS homologue from salivary glands of Ixodes persulcatus Schulze]
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Identification and the preliminary in vitro characterization of IRIS homologue from salivary glands of Ixodes persulcatus Schulze
Background Although vector control strategies, such as insecticide-treated bed nets (ITNs) and indoor residual spraying (IRS) have been effective in Kenya the transmission of malaria continues to afflict western Kenya. This residual transmission is driven in part by Anopheles arabiensis, known fo...
Lozano-Fuentes, Saul
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Kading, R.C.
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Hartman, D.A.
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Okoth, Edward A.
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Githaka, Naftaly W.
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Nene, Vishvanath
,
Poche, R.M.
,
[Evaluation of a topical formulation of eprinomectin against Anopheles arabiensis when administered to Zebu cattle (Bos indicus) under field conditions]
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Evaluation of a topical formulation of eprinomectin against Anopheles arabiensis when administered to Zebu cattle (Bos indicus) under field conditions
Background
Rhipicephalus appendiculatus is the primary vector of Theileria parva, the etiological agent of East Coast fever (ECF), a devastating disease of cattle in sub-Saharan Africa. We hypothesized that a vaccine targeting tick proteins that are involved in attachment and feeding might affect...
Olds, Cassandra L.
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Mwaura, S.
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Odongo, David O.
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Scoles, Glen A.
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Bishop, R.
,
Daubenberger, C.A.
,
[Induction of humoral immune response to multiple recombinant Rhipicephalus appendiculatus antigens and their effect on tick feeding success and pathogen transmission]
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Induction of humoral immune response to multiple recombinant Rhipicephalus appendiculatus antigens and their effect on tick feeding success and pathogen transmission
Influenza D virus has been identified in America, Europe, and Asia. We detected influenza D virus antibodies in cattle and small ruminants from North (Morocco) and West (Togo and Benin) Africa. Dromedary camels in Kenya harbored influenza C or D virus antibodies, indicating a potential new host f...
Salem, E.
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Cook, Elizabeth A.J.
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Lbacha, H.A.
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Oliva, J.
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Awoume, F.
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Aplogan, G.L.
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Hymann, E.C.
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Muloi, D.
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Deem, S.L.
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Alali, S.
,
Zouagui, Z.
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Fèvre, Eric M.
,
Meyer, G.
,
Ducatez, M.F.
,
[Serologic evidence for influenza C and D virus among ruminants and camelids, Africa, 1991–2015]
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Serologic evidence for influenza C and D virus among ruminants and camelids, Africa, 1991–2015
Global risks of zoonotic disease are high on policy agendas. Increasingly, Africa is seen as a ‘hotspot’, with likely disease spillovers from animals to humans. This paper explores the social dynamics of disease exposure, demonstrating how risks are not generalised, but are related to occupation,...
Dzingirai, V.
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Bett, Bernard K.
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Bukachi, S.A.
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Lawson, E.
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Mangwanya, L.
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Scoones, I.
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Waldman, L.
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Wilkinson, A.
,
Leach, M.
,
Winnebah, T.R.A.
,
[Zoonotic diseases: who gets sick, and why? Explorations from Africa]
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Zoonotic diseases: who gets sick, and why? Explorations from Africa
In Vietnam, Japanese encephalitis virus accounts for 12–71% of viral encephalitis (VE) cases followed by enteroviruses and dengue virus among identified pathogens. This study is the first attempt to evaluate the seasonality of VE and associated environmental risk factors in two provinces from 200...
Hu Suk Lee
,
Hung Nguyen-Viet
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Lee, M.
,
Phuc Pham Duc
,
Grace, Delia
,
[Seasonality of viral encephalitis and associated environmental risk factors in Son La and Thai Binh provinces in Vietnam from 2004 to 2013]
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Seasonality of viral encephalitis and associated environmental risk factors in Son La and Thai Binh provinces in Vietnam from 2004 to 2013
Teshager, N.
,
[Pathological and sero-epidemiological study of infectious bursal disease on small holder chickens around Bahirdar]
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Pathological and sero-epidemiological study of infectious bursal disease on small holder chickens around Bahirdar
Urbanization is characterized by rapid intensification of agriculture, socioeconomic change, and ecological fragmentation, which can have profound impacts on the epidemiology of infectious disease. Here, we review current scientific evidence for the drivers and epidemiology of emerging wildlife-b...
Hassell, J.M.
,
Begon, M.
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Ward, M.J.
,
Fèvre, Eric M.
,
[Urbanization and disease emergence: Dynamics at the wildlife–livestock–human interface]
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Urbanization and disease emergence: Dynamics at the wildlife–livestock–human interface
During 2014–2015, patients in northeastern Kenya were assessed for brucellosis and characteristics that might help clinicians identify brucellosis. Among 146 confirmed brucellosis patients, 29 (20%) had negative serologic tests. No clinical feature was a good indicator of infection, which was ass...
Njeru, J.
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Melzer, F.
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Wareth, G.
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El-Adawy, H.
,
Henning, K.
,
Pletz, M.W.
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Heller, R.
,
Kariuki, S.
,
Fèvre, Eric M.
,
Neubauer, H.
,
[Human brucellosis in febrile patients seeking treatment at remote hospitals, northeastern Kenya, 2014–2015]
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Human brucellosis in febrile patients seeking treatment at remote hospitals, northeastern Kenya, 2014–2015