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Heme Oxygenase 1 (HMOX1) is an enzyme that catalyzes the reaction that degrades the heme group contained in several important proteins, such as hemoglobin, myoglobin, and cytochrome p450. The enzymatic reaction catalyzed by HMOX1 generates Fe2+, biliverdin and CO. It has been shown that HMOX1 act...


Sebastián, V.P.Salazar, G.A.Coronado-Arrázola, I.Schultz, B.M.Vallejos, O.P.Berkowitz, L.Álvarez-Lobos, M.M.Riedel, C.A.Kalergis, A.M.Bueno, S.M.[Heme oxygenase-1 as a modulator of intestinal inflammation development and progression]Heme oxygenase-1 as a modulator of intestinal inflammation development and progression

The human body is colonized by millions of microorganisms named microbiota that interact with our tissues in a cooperative and non-pathogenic manner. These microorganisms are present in the skin, gut, nasal, oral cavities, and genital tract. In fact, it has been described that the microbiota cont...


Opazo, M.C.Ortega-Rocha, E.M.Coronado-Arrázola, I.Bonifaz, L.C.Boudin, H.Neunlist, M.Bueno, S.M.Kalergis, A.M.Riedel, C.A.[Intestinal microbiota influences non-intestinal related autoimmune diseases]Intestinal microbiota influences non-intestinal related autoimmune diseases

The human microbiome participates in numerous aspects of human physiology and disease states. Recently, studies have begun to explore the role of the microbiome in colonization, infection and transmission of pathogens. This review provides a summary of the methodological principles used in microb...


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