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Innes, E.A.Brown, C.G.D.Spooner, R.L.[Comparative immunobiology of Theileria annulata and Theileria parva]Comparative immunobiology of Theileria annulata and Theileria parva
International Livestock Centre for Africa[Inauguration Symposium on Current Trends in Immunology and Genetics and Their Implications for Parasitic Diseases]Inauguration Symposium on Current Trends in Immunology and Genetics and Their Implications for Parasitic Diseases
Morales, Francisco JoséCastaño J., MauricioCalvert, Lee A.Arroyave, José A.[Furcraea necrotic streak virus : an apparent new member of the dianthovirus group]Furcraea necrotic streak virus : an apparent new member of the dianthovirus group

Rift Valley fever virus (RVFV) is an important mosquito-borne pathogen with devastating impacts on agriculture and public health. With outbreaks being reported beyond the continent of Africa to the Middle East, there is great concern that RVFV will continue to spread to non-endemic areas such as ...


Lindahl, Johanna F.Ragan, I.Rowland, R.R.Wainaina, M.Mbotha, D.Wilson, W.[A multiplex fluorescence microsphere immunoassay for increased understanding of Rift Valley fever immune responses in ruminants in Kenya]A multiplex fluorescence microsphere immunoassay for increased understanding of Rift Valley fever immune responses in ruminants in Kenya

Three international workshops held over the past eight years have addressed the identification and nomenclature of leukocyte differentiation antigens in ruminants. This article explains the progress the workshops have made.


Naessens, JanHoward, C.J.Hopkins, J.[Nomenclature and characterization of leukocyte differentiation antigens in ruminants]Nomenclature and characterization of leukocyte differentiation antigens in ruminants

The first visible response in livestock to the bite of a trypanosome-infected tsetse fly is the formation of a localized skin reaction, also known as a chancre. This is an inflammatory response in the skin associated with swelling and an influx of cells. It is thought to be associated with an a...


Naessens, JanMwangi, D.M.Buza, J.Moloo, S.K.[Local skin reaction (chancre) induced following inoculation of metacyclic trypanosomes in cattle by tsetse flies is dependent on CD4 T lymphocytes]Local skin reaction (chancre) induced following inoculation of metacyclic trypanosomes in cattle by tsetse flies is dependent on CD4 T lymphocytes

From a lysate of radiolabeled Theileria parva-infected bovine lymphocytes monoclonal antibody (mAb) IL-A77 immunoprecipitated a molecule of Mr 190 000 under non-reducing conditions, which was shown to be a homodimer of a Mr 90 000 protein after reduction (Naessens et al., 1996). Purification of t...


Naessens, JanDavis, W.C.[Ruminant cluster CD71]Ruminant cluster CD71

A hybridoma cell line has been previously produced which secretes monoclonal antibodies that neutralize sporozoites of T. parva. Cells from this line were injected i/p into pristane-treated BALB/c mice. During the last 4 days of hybridoma cell growth, mice were given 4 daily i/p injections of a m...


Dobbelaere, D.A.E.Spooner, P.R.[Production in ascites fluid of biosynthetically labelled monoclonal antibody to Theileria parva sporozoites]Production in ascites fluid of biosynthetically labelled monoclonal antibody to Theileria parva sporozoites

Dendritic cells (DC) constitute the most effective immune cell population for priming and recalling T cell responses to foreign antigens. DC patrol the peripheral tissues collecting foreign antigen for subsequent presentation by classical class II MHC molecules to T cells in the draining lymph no...


Ballingall, K.T.MacHugh, Niall D.Taracha, E.L.N.Mertens, B.McKeever, B.D.[Transcription of the unique ruminant class II major histocompatibility complex-DYA and DIB genes in dendritic cells]Transcription of the unique ruminant class II major histocompatibility complex-DYA and DIB genes in dendritic cells

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