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Reviews prospects of vaccination against African trypanosomiasis, mentioning constraints in developing a vaccine, and current knowledge on the molecular biology of the trypanosome and on antigenic variation with respect to possible future vaccines. Describes possible regimes for immunological int...
The genetic components of trypanotolerance measurements must be determined in well controlled on going production systems where the necessary identification and/or quantification of environment and genetic effects are possible. A resource population has been established in the Mushie District Ban...
Inbred strains of laboratory mice exhibit marked differences in survival time following infection with Trypanosoma congolense, the principal cause of trypanosomiasis in African livestock.The difference in survival time between the relatively resistant C57BL/6 J and more susceptible BALB/c inbred ...
Natural resistance to African trypanosomiasis in certain Bos taurus cattle in West Africa, called trypanotolerance, may hold solutions for control of this economically crippling disease. Comparison of immune responses between trypanotolerant and trypanosusceptible cattle have shown some differenc...
It is known that different breeds of cattle display differential susceptibilities to Trypanosome congolense infections, and that N'Dama cattle remain more productive after infection than Boran cattle which are more susceptible to T. congolense. Macrophages from both breeds were cultured in vitro ...
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