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Grab, D.J.Baldwin, C.L.Brown, W.C.Innes, E.A.Lonsdale-Eccles, J.D.Verjee, Y.[Immune CD4+ T cells specific for Theileria parva-infected lymphocytes recognize a 24-kilodalton protein]Immune CD4+ T cells specific for Theileria parva-infected lymphocytes recognize a 24-kilodalton protein

Heterologous priming-boosting vaccination regimens involving priming with plasmid DNA antigen constructs and inoculating (boosting) with the same recombinant antigen expressed in replication-attenuated poxviruses have recently been demonstrated to induce immunity, based on CD4(+)- and CD8(+)-T-c...


Taracha, E.L.N.Bishop, Richard P.Musoke, A.J.Hill, A.V.S.Gilbert, S.C.[Heterologous priming-boosting immunization of cattle with Mycobacterium tuberculosis 85A induces antigen-specific T-cell responses]Heterologous priming-boosting immunization of cattle with Mycobacterium tuberculosis 85A induces antigen-specific T-cell responses

Theileria parva causes an acute lympho-proliferative disease in cattle, which can result in death of susceptible animals within 2-3 weeks of infection. Analyses of the cellular response in the lymph node draining the site of infection demonstrated an early T cell response, with the appearance of ...


Houston, E.F.Taracha, E.L.N.Brackenbury, L.MacHugh, Niall D.McKeever, Declan J.Charleston, B.Morrison, W. Ivan[Infection of cattle with Theileria parva induces an early CD8 T cell response lacking appropriate effector function]Infection of cattle with Theileria parva induces an early CD8 T cell response lacking appropriate effector function
Kachani, M.Spooner, R.L.[Anti-lymphocyte antibodies generated in animals immunised wtih Theileria annulata infected cells]Anti-lymphocyte antibodies generated in animals immunised wtih Theileria annulata infected cells
Morrison, W. IvanGoddeeris, M.Brown, W.C.Baldwin, C.L.Teale, A.J.[Theileria parva in cattle: Characterization of infected lymphocytes and the immune responses they provoke]Theileria parva in cattle: Characterization of infected lymphocytes and the immune responses they provoke

The importance of T-cell-mediate immune responses in the control of intracellular protozoan parasites is now well established 1-3. The killing of parasitized cells by T cells and cytokine-mediated effects on growth and viability of the intracellular parasites have both been implicated as effector...


Morrison, W. IvanTaracha, E.L.N.McKeever, Declan J.[Contribution of T-cell responses to immunity and pathogenesis in infection with Theileria parva]Contribution of T-cell responses to immunity and pathogenesis in infection with Theileria parva
Ole-MoiYoi, O.K.Sugimoto, C.Conrad, P.A.Macklin, M.D.[Cloning and characterization of the casein kinase II alpha subunit gene from the lymphocyte-transforming intracellular protozoan parasite Theileria parva]Cloning and characterization of the casein kinase II alpha subunit gene from the lymphocyte-transforming intracellular protozoan parasite Theileria parva
Mayor-Withey, K.S.Clayton, C.E.Roelants, G.E.Askonas, B.A.[Trypanosomiasis leads to extensive proliferation of B, T and null cells in spleen and bone marrow]Trypanosomiasis leads to extensive proliferation of B, T and null cells in spleen and bone marrow
Morrison, W. IvanRoelants, G.E.Mayor-Withey, K.S.Murray, M.[Susceptibility of inbred strains of mice to Trypanosoma congolense. Correlation with changes in spleen lymphocyte populations]Susceptibility of inbred strains of mice to Trypanosoma congolense. Correlation with changes in spleen lymphocyte populations

A flow cytometric method using anti-parasite antibodies was developed to measure binding of theileria parva sporozoites to the target bovine lymphocyte membrane. Parasite-host cell interactions could be inhibited by monoclonal antibodies to bovine MHC class I and partially by one of two antibodie...


Syfrig, J.Wells, C.Daubenberger, C.A.Musoke, A.J.Naessens, Jan[Proteolytic cleavage of surface proteins enhances susceptibility of lymphocytes to invasion by Theileria parva sporozoites]Proteolytic cleavage of surface proteins enhances susceptibility of lymphocytes to invasion by Theileria parva sporozoites

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