In this paper genomic research is discussed with regard to prospects for improving livestock productivity. Topics of discussion include, constraints to livestock productivity in developing countries; biotechnology research at ILRI; improvement of rumen fermentation; livestock genetic resources an...
Contagious bovine pleuropneumonia (CBPP) is one of the most important transboundary animal diseases in Africa. In recent years, CBPP has been found in countries like Botswana from where it was previously eradicated (Amanfu et al., 1998). There is growing evidence to indicate that the incidence of...
We describe the development of TparvaDB, a comprehensive resource to facilitate research towards development of an East Coast fever vaccine, by providing an integrated user-friendly database of all genome and related data currently available for Theileria parva. TparvaDB is based on the Generic M...
Visendi, P.
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Ng'ang'a, W.
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Bulimo, Wallace
,
Bishop, Richard P.
,
Ochanda, J.
,
Villiers, Etienne P. de
,
[TparvaDB: A database to support Theileria parva vaccine development]
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TparvaDB: A database to support Theileria parva vaccine development
The eradication of smallpox (variola) and the subsequent cessation of routine vaccination have left modern society vulnerable to bioterrorism employing this devastating contagious disease. The existing, licensed vaccines based on live vaccinia virus (VACV) are contraindicated for a substantial nu...
Lantto, J.
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Hansen, M.H.
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Rasmussen, S.K.
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Steinaa, Lucilla
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Poulsen, T.R.
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Duggan, J.
,
Dennis, M.
,
Naylor, I.
,
Easterbrook, L.
,
Bregenholt, S.
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Haurum, J.
,
Jensen, A.
,
[Capturing the natural diversity of the human antibody response against vaccinia virus]
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Capturing the natural diversity of the human antibody response against vaccinia virus
L’élevage au Mali rencontre de nombreuses difficultés pour son essor. Parmi elles, les difficultés d’ordre sanitaire causées particulièrement par la grande prévalence de maladies contagieuses, endémiques suite à une mauvaise couverture vaccinale lors des différentes campagnes de vaccination dans ...
Sadio, Y.A.
,
[Etude des facteurs affectant la vaccination des ruminants domestiques dans les régions de Sikasso et Mopti, Mali]
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Etude des facteurs affectant la vaccination des ruminants domestiques dans les régions de Sikasso et Mopti, Mali
The major sporozoite surface antigen of Theileria annulata (SPAG-1) is a candidate for inclusion in a subunit vaccine. In this paper we summarize the results of 4 vaccination experiments using recombinant SPAG-1 expressed in different systems and presented in different adjuvants. The antigen has ...
Boulter, N.
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Brown, D.
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Wilkie, G.
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Williamson, S.
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Kirvar, E.
,
Knight, P.
,
Glass, E.
,
Campbell, J.
,
Morzaria, S.P.
,
Nene, Vishvanath
,
Musoke, A.J.
,
Oliveria, C. de
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Gubbels, M.J.
,
Jongejan, F.
,
Hall, R.
,
[Evaluation of recombinant sporozoite antigen SPAG-1 as a vaccine candidate against Theileria annulata by the use of different delivery systems]
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Evaluation of recombinant sporozoite antigen SPAG-1 as a vaccine candidate against Theileria annulata by the use of different delivery systems
Theileria parva, a protozoan parasite of cattle, causes a disease called East Coast fever. The disease is of economic importance because it causes high morbidity and mortality and limits the development of the cattle industry. This paper highlights the experiences with immunization against Theile...
Musoke, A.J.
,
McKeever, Declan J.
,
Morzaria, S.P.
,
Nkonge, C.
,
Nene, Vishvanath
,
[Experiences with immunization against Theileria parva using p67, a sporozoite surface antigen]
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Experiences with immunization against Theileria parva using p67, a sporozoite surface antigen
Techniques for in vivo depletion of lymphocytes using monoclonal antibodies have been well documented for murine systems. This model has played an important role in analysing the involvement of various lymphocyte subsets in several immune mechanisms. In mice 600 ug of Ab are generally injected in...