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Theileria parva, a tick-borne api-complexan protozoan parasite, causes East Coast fever (ECF) in cattle. Control of the disease by improved vaccination is believed to provide a sustainable solution. Class I MHC-restricted CD8+ cytotoxic T lymphocytes (CTL) directed at schizontinfected cells const...
East Coast Fever (ECF) is a major risk and constraint to the smallholder dairy sector in Kenya. The effects of ECF can be largely controlled by the use of acaricides, animal husbandry measures, and potentially through immunisation. In Kenya, some smallholder dairy farmers apply one or more of the...
In this paper genomic research is discussed with regard to prospects for improving livestock productivity. Topics of discussion include, constraints to livestock productivity in developing countries; biotechnology research at ILRI; improvement of rumen fermentation; livestock genetic resources an...
The "Muguga cocktail" live vaccine comprises three Theileria parva stocks (Muguga, Kiambu 5 and the buffalo-derived Serengeti-transformed) and has been used extensively in Eastern, Central and Southern Africa with an infection and treatment protocol to protect cattle against East Coast fever. We ...
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