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Paling, R.W.Moloo, S.K.Jenni, L.[Trypanosoma congolense. Host responses following tsetse transmitted infection of Kilifi isolates in goats]Trypanosoma congolense. Host responses following tsetse transmitted infection of Kilifi isolates in goats

In part I of this review of the prospects of vaccination against African trypanosomiasis, contained in the previous issue of World Animal Review, the constraints in developing a vaccine were discussed and current knowledge on the molecular biology of the trypanosome and on antigenic variation wit...


Murray, M.Barry, J.D.Morrison, W. IvanWilliams, R.O.Hirumi, H.Rovis, L.A.[A review of the prospects for vaccination in African trypanosomiasis. Part II]A review of the prospects for vaccination in African trypanosomiasis. Part II

Immunity to infection by the protozoan parasite Theileria parva in cattle is partially attributable to cytotoxic T cells, which kill lymphocytes infected with the schizont stage of the parasite. Here we evaluated five stocks of buffalo-derived T. parva lawrencei parasites and two stocks of cattle...


Kariuki, T.M.Grootenhuis, J.G.Dolan, T.T.Bishop, Richard P.Baldwin, C.L.[Immunization with Theileria parva parasites from buffaloes results in generation of cytotoxic T cells which recognize antigens common among cells infected with stocks of T. parva parva, T. parva bovis, and T. parva lawrencei]Immunization with Theileria parva parasites from buffaloes results in generation of cytotoxic T cells which recognize antigens common among cells infected with stocks of T. parva parva, T. parva bovis, and T. parva lawrencei
Baldwin, C.L.Malu, M.N.Kinuthia, S.W.Conrad, P.A.Grootenhuis, J.G.[Comparative analysis of infection and transformation of lymphocytes from African buffalo and Boran cattle with Theileria parva subsparva and Theileria parva subslawrencei]Comparative analysis of infection and transformation of lymphocytes from African buffalo and Boran cattle with Theileria parva subsparva and Theileria parva subslawrencei
Demartini, J.C.Baldwin, C.L.[Effects of gamma interferon, tumor necrosis factor alpha and interleukin-2 on infection and proliferation of Theileria parva- infected bovine lymphoblasts and production of interferon by parasitized cells]Effects of gamma interferon, tumor necrosis factor alpha and interleukin-2 on infection and proliferation of Theileria parva- infected bovine lymphoblasts and production of interferon by parasitized cells
Nantulya, V.M.Musoke, A.J.Moloo, S.K.[Apparent exhaustion of the variable antigen repertoires of Trypanosoma vivax in infected cattle]Apparent exhaustion of the variable antigen repertoires of Trypanosoma vivax in infected cattle
Shapiro, S.Z.Black, S.J.[Identification of an acute-phase reactant in murine infections with Trypanosoma brucei]Identification of an acute-phase reactant in murine infections with Trypanosoma brucei

Infection with African trypanosomes causes the diseases sleeping sickness in humans and nagana in cattle in sub-Saharan Africa. Suppression of cellular immune responses is a feature of trypanosomiasis in bovine, human, and murine hosts. Some aspects of immunosuppression in the murine model are me...


Taylor, K.Lutje, V.Mertens, B.[Nitric Oxide synthesis is depressed in Bos indicus cattle infected with Trypanosoma congolense and Trypanosoma vivax and does not mediate T-cell suppression]Nitric Oxide synthesis is depressed in Bos indicus cattle infected with Trypanosoma congolense and Trypanosoma vivax and does not mediate T-cell suppression

Theileria parva causes an acute lympho-proliferative disease in cattle, which can result in death of susceptible animals within 2-3 weeks of infection. Analyses of the cellular response in the lymph node draining the site of infection demonstrated an early T cell response, with the appearance of ...


Houston, E.F.Taracha, E.L.N.Brackenbury, L.MacHugh, Niall D.McKeever, Declan J.Charleston, B.Morrison, W. Ivan[Infection of cattle with Theileria parva induces an early CD8 T cell response lacking appropriate effector function]Infection of cattle with Theileria parva induces an early CD8 T cell response lacking appropriate effector function
Nyeko, J.H.P.Ole-MoiYoi, O.K.Majiwa, P.A.O.Otieno, L.H.Ociba, P.M.[Characterization of Trypanosoma isolates from cattle in Uganda using species-specific DNA probes reveals predominace of mixed infection]Characterization of Trypanosoma isolates from cattle in Uganda using species-specific DNA probes reveals predominace of mixed infection

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