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The aim of the present work was to study the cycle of transmission of T. b rhodesiense clone Etat 1/10 by G. morsitans from an infected bushbuck (Tragelaphus scriptus) to a Boran steer (Bos indicus), a goat (Capra hirci) and, by tsetse, from the infected domestic ruminants to bushbuck. The sensit...


Moloo, S.K.Grootenhuis, J.G.Jenni, L.Brun, R.Meirvenne, N. vanMurry, M.[Trypanosoma brucei rhodesience: Variation in human serum resistance after transmission between bushbuck and domestic ruminants by Glossina morsitans morsitans]Trypanosoma brucei rhodesience: Variation in human serum resistance after transmission between bushbuck and domestic ruminants by Glossina morsitans morsitans
Ellis, J.A.Fish, W.R.Sileghem, M.R.McOdimba, F.A.[A calorimetric assay for trypanosome viability and metabolic function]A calorimetric assay for trypanosome viability and metabolic function
Komba, E.Odiit, M.Mbulamberi, D.B.Chimfwembe, E.C.Nantulya, V.M.[Multicentre evaluation of an antigen-detection ELISA for the diagnosis of Trypanosoma brucei rhodesiense sleeping sickness]Multicentre evaluation of an antigen-detection ELISA for the diagnosis of Trypanosoma brucei rhodesiense sleeping sickness

Background: The expansion of sleeping sickness caused by Trypanosoma brucei rhodesiense (T. rhodesiense) beyond its traditional focus in southeast Uganda, has been linked with large-scale livestock restocking. To assess the risk presented to the human population by domestic livestock, human-infe...


Welburn, S.C.Picozzi, K.Fèvre, Eric M.Coleman, P.G.Odiit, M.Carrington, M.Maudlin, I.[Identification of human-infective trypanosomes in animal reservoir of sleeping sickness in Uganda by means of serum-resistance-associated (SRA) gene]Identification of human-infective trypanosomes in animal reservoir of sleeping sickness in Uganda by means of serum-resistance-associated (SRA) gene

Geographic information systems (GIS) and remote sensing were used to identify villages at high risk for sleeping sickness, as defined by reported incidence. Landsat Enhanced Thematic Mapper (ETM) satellite data were classified to obtain a map of land cover, and the Normalised Difference Vegetatio...


Odiit, M.Bessell, P.R.Fèvre, Eric M.Robinson, Timothy P.Kinoti, J.Coleman, P.G.Welburn, S.C.McDermott, John J.Woolhouse, Mark E.J.[Using remote sensing and geographic information systems to identify villages at high risk for rhodesiense sleeping sickness in Uganda]Using remote sensing and geographic information systems to identify villages at high risk for rhodesiense sleeping sickness in Uganda
Nantulya, V.M.[Immunodiagnosis of rhodesiense sleeping sickness: Detection of circulating trypanomal antigens in sera and cerebrospinal fluid by enzyme immunoassay using a monoclonal antibody]Immunodiagnosis of rhodesiense sleeping sickness: Detection of circulating trypanomal antigens in sera and cerebrospinal fluid by enzyme immunoassay using a monoclonal antibody

To formally quantify the level of under-detection of Trypanosoma brucei rhodesiense sleeping sickness (SS) during an epidemic in Uganda, a decision tree (under-detection) model was developed; concurrently, to quantify the subset of undetected cases that sought health care but were not diagnosed, ...


Odiit, M.Coleman, P.G.Liu, W.C.McDermott, John J.Fèvre, Eric M.Welburn, S.C.Woolhouse, Mark E.J.[Quantifying the level of under-detection of Trypanosoma brucei rhodesiense sleeping sickness cases]Quantifying the level of under-detection of Trypanosoma brucei rhodesiense sleeping sickness cases

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