Trypanosomiasis remains the most important constraint to livestock production on the African continent. Chemotherapy, using curative and prophylactic drugs, is the main method of control of the disease in cattle. The exploitation of the trypanotolerance trait of some breeds of large and small rum...
Vreysen, M.J.B.
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Leak, S.G.A.
,
[Tsetse control: Recent successes in Tanzania and Ethiopia]
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Tsetse control: Recent successes in Tanzania and Ethiopia
Nantulya, V.M.
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Bajyana Songa, E.
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Hamers, R.
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[Detection of circulating trypanosomal antigen in Trypanosoma evansi-infected animals using a Trypanosoma brucei group-specific monoclonal antibody]
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Detection of circulating trypanosomal antigen in Trypanosoma evansi-infected animals using a Trypanosoma brucei group-specific monoclonal antibody
Mice were immunized with either an isometamidium-human serum albumin (HSA) conjugate or an isometamidium-porcine thyroglobulin conjugate (PTG). Thereafter, monoclonal antibodies (MAbs) IL-A 1001, IL-A 1002, IL-A 1003, 5F7.B7, and 5F7.C9 were generated and selected on the basis that they recognize...
Peregrine, A.S.
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Eisler, M.C.
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Katende, J.
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Flynn, J.N.
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Gault, E.A.
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Kinabo, L.D.B.
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Holmes, P.H.
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[Generation of monoclonal antibodies to the anti-trypanosomal drug isometamidium]
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Generation of monoclonal antibodies to the anti-trypanosomal drug isometamidium
Over the past few years, research at ILRI and by its partners has identified genomic regions controlling trypanotolerance in cattle and in mice. In mice many of the genes lying within these genomic regions have been identified, leading the way to identification of the genes controlling trypanotol...
Inverso, J.A.
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Gee, A.L.W. de
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Mansfield, J.M.
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[Genetics of resistance to the African trypanosomes. VII. Trypanosome virulence is not linked to variable surface glycoprotein expression]
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Genetics of resistance to the African trypanosomes. VII. Trypanosome virulence is not linked to variable surface glycoprotein expression
African trypanosomes are protozoan parasites that cause “sleeping sickness” in humans and a similar disease in livestock. Trypanosomes also infect laboratory mice and three major quantitative trait loci (QTL) that regulate survival time after infection with T. congolense have been identified in t...
Goodhead, I.
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Archibald, A.L.
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Amwayi, P.
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Brass, A.
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Gibson, John P.
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Hall, N.
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Hughes, Monica A.
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Limo, M.K.H.
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Iraqi, F.A.
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Kemp, Stephen J.
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Noyes, H.A.
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[A comprehensive genetic analysis of candidate genes regulating response to Trypanosoma congolense infection in mice]
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A comprehensive genetic analysis of candidate genes regulating response to Trypanosoma congolense infection in mice
This study was conducted to identify the 6 major criteria that periurban dairy producers of the subhumid zone of Burkina Faso use in upstream decisions on breed composition of their herds through the repertory grid method. This study was carried out in a sample of 283 producers of Bobo-Dioulas...
Hamadou, S.
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Kamuanga, M.
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[Farmers' perceptions and assessment of cattle traits in periurban dairy systems of Bobo-Dioulasso (Burkina Faso)]
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Farmers' perceptions and assessment of cattle traits in periurban dairy systems of Bobo-Dioulasso (Burkina Faso)
High-resolution mapping of quantitative trait loci (QTLs) is an essential step towards positional cloning and identification of the corresponding genes. Most QTL detection and mapping studies in mice have been carried out using F2 intercross and backcross populations. As a consequence of the limi...
Iraqi, F.A.
,
[Fine mapping of quantitative trait loci using advanced intercross lines of mice and positional cloning of the corresponding genes]
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Fine mapping of quantitative trait loci using advanced intercross lines of mice and positional cloning of the corresponding genes
Sileghem, M.R.
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Flynn, J.N.
,
[Suppression of interleukin 2 secretion and interleukin 2 receptor expression during tsetse-transmitted trypanosomiasis in cattle]
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Suppression of interleukin 2 secretion and interleukin 2 receptor expression during tsetse-transmitted trypanosomiasis in cattle