The first visible response in livestock to the bite of a trypanosome-infected tsetse fly is the formation of a localized skin reaction, also known as a chancre. This is an inflammatory response in the skin associated with swelling and an influx of cells. It is thought to be associated with an a...
Naessens, Jan
,
Mwangi, D.M.
,
Buza, J.
,
Moloo, S.K.
,
[Local skin reaction (chancre) induced following inoculation of metacyclic trypanosomes in cattle by tsetse flies is dependent on CD4 T lymphocytes]
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Local skin reaction (chancre) induced following inoculation of metacyclic trypanosomes in cattle by tsetse flies is dependent on CD4 T lymphocytes
Development of anaemia in inflammatory diseases is cytokine-mediated. Specifically, the levels of tumour necrosis factor-alpha (TNF-alpha), produced by activated macrophages, are correlated with severity of disease and anaemia in infections and chronic disease. In African trypanosomiasis, anaemia...
Naessens, Jan
,
Kitani, H.
,
Nakamura, Y.
,
Yagi, Y.
,
Sekikawa, K.
,
Iraqi, F.A.
,
[TNF-alpha mediates the development of anaemia in a murine Trypanosoma brucei rhodesiense infection, but not the anaemia associated with a murine Trypanosoma congolense infection]
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TNF-alpha mediates the development of anaemia in a murine Trypanosoma brucei rhodesiense infection, but not the anaemia associated with a murine Trypanosoma congolense infection
C57BL/6 mice deficient in one or two copies of the gene for tumor necrosis factor alpha (TNF-alpha) were more susceptible to Trypanosoma congolense infection than their resistant, wild-type counterparts. The number of TNF-alpha genes was correlated with the capacity to control parasitaemia and ...
Naessens, Jan
,
Kitani, H.
,
Momotani, E.
,
Sekikawa, K.
,
Nthale, J.M.
,
Iraqi, F.A.
,
[Susceptibility of TNF-alpha-deficient mice to Trypanosoma congolense is not due to a defective antibody response]
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Susceptibility of TNF-alpha-deficient mice to Trypanosoma congolense is not due to a defective antibody response
Naessens, Jan
,
Williams, D.J.L.
,
[Characterization and measurement of CD5+ B cells in normal and Trypanosoma congolense- infected cattle]
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Characterization and measurement of CD5+ B cells in normal and Trypanosoma congolense- infected cattle
Dwinger, R.H.
,
Luckins, G.
,
Murray, M.
,
Rae, P.
,
Moloo, S.K.
,
[Interference between different serodemes of Trypanosoma congolense in the establishment of superinfections in goats following transmission by tsetse]
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Interference between different serodemes of Trypanosoma congolense in the establishment of superinfections in goats following transmission by tsetse
Morrison, W. Ivan
,
Murray, M.
,
[The role of humoral immune responses in determining susceptibility of A/J and C57BL/6 mice to infection with Trypanosoma congolense]
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The role of humoral immune responses in determining susceptibility of A/J and C57BL/6 mice to infection with Trypanosoma congolense
Examines the development and the ultrastructural and histological distribution of Trypanosoma congolense, T Vivax and T brucei in the skin of goats in Kenya, after the animals were bitten by infected Glossina morsitans centralis.
Dwinger, R.H.
,
Murray, M.
,
[Development of Trypanosoma congolense, T. vivax and T. brucei in the skin reaction induced in goats by infected Glossina morsitans centralis: A light and electron microscopical study]
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Development of Trypanosoma congolense, T. vivax and T. brucei in the skin reaction induced in goats by infected Glossina morsitans centralis: A light and electron microscopical study
Andrianarivo, A.G.
,
Muiya, P.
,
McOdimba, F.A.
,
Gettinby, G.
,
Logan-Henfrey, L.L.
,
[Kinetics of haemopoietic progenitor cell during a Trypanosoma congolense rechallenge infection in Boran cattle]
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Kinetics of haemopoietic progenitor cell during a Trypanosoma congolense rechallenge infection in Boran cattle
Authié, E.
,
Muteti, D.K.
,
Williams, D.J.L.
,
[Antibody responses to invariant antigens of Trypanosoma congolense in cattle of differing susceptibility to trypanosomiasis]
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Antibody responses to invariant antigens of Trypanosoma congolense in cattle of differing susceptibility to trypanosomiasis