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Theileria parva, a protozoan parasite of cattle, causes a disease called East Coast fever. The disease is of economic importance because it causes high morbidity and mortality and limits the development of the cattle industry. This paper highlights the experiences with immunization against Theile...


Musoke, A.J.McKeever, Declan J.Morzaria, S.P.Nkonge, C.Nene, Vishvanath[Experiences with immunization against Theileria parva using p67, a sporozoite surface antigen]Experiences with immunization against Theileria parva using p67, a sporozoite surface antigen

Theileria parva is an intracellular protozoan parasite that infects and transforms bovine lymphocytes, causing a severe Iymphoproliferative disease, East Coast fever (ECF). A robust immunity against ECF acquired after recovery is thought to be conferred by cytotoxic T lymphocytes (CTLs) specific ...


Mwakubambanya, R.S.[Identification of Bola Class I molecules restricting cytotoxic T lymphocyte responses to a theileria parva vaccine candidate.]Identification of Bola Class I molecules restricting cytotoxic T lymphocyte responses to a theileria parva vaccine candidate.
Autor: Maina, P.

Packed cell volume were measured by centrifugation for 6 mm. In the Hawksley microhaematocrit using blood collected from the Jugular vein. Haemoglobin estimation expressed as percentage differential white cell counts were made from thinblood smears counting 400 cells per smear were possible using...


Maina, P.[Pathogenesis of lung oedema in cattle infected with theileria parva (Muguga).]Pathogenesis of lung oedema in cattle infected with theileria parva (Muguga).
Glaser, I.[Herstelling eines lebendimpfstoffes gegen theileria parva auf der basis von attenuierten salmonellen.]Herstelling eines lebendimpfstoffes gegen theileria parva auf der basis von attenuierten salmonellen.

Immunity to the bovine apicomplexan parasite Theileria parva is associated with MHC-I restricted CD8+ T cell responses directed against the intralymphocytic schizont stage of the parasite. A number of schizont-stage antigens that are targets of CD8+ T cell responses from immune animals have been ...


Tinega, A.N.Pelle, RogerKang'a, S.Gicheru, M.M.Taracha, E.L.N.Nene, VishvanathGraham, S.P.[Fusion of a cell penetrating peptide from HIV-1 TAT to the Theileria parva antigen Tp2 enhances the stimulation of bovine CD8+ T cell responses]Fusion of a cell penetrating peptide from HIV-1 TAT to the Theileria parva antigen Tp2 enhances the stimulation of bovine CD8+ T cell responses

The protozoan parasite Theileria parva causes a usually fatal disease in cattle, known as East Coast fever. Cattle can be vaccinated by injecting live parasites simultaneously with long acting oxytetracycline (the Infection and Treatment Method, ITM). The immunity induced by ITM is believed to be...


Steinaa, LucillaSaya, R.Awino, EliasToye, Philip G.[Cytotoxic T lymphocytes from cattle immunized against Theileria parva exhibit pronounced cross-reactivity among different strain-specific epitopes of the Tp1 antigen]Cytotoxic T lymphocytes from cattle immunized against Theileria parva exhibit pronounced cross-reactivity among different strain-specific epitopes of the Tp1 antigen
Irvin, A.D.Morzaria, S.P.[Report on a Mission to Isolate Theileria parva in Zanzibar and to Assess the Feasability of Conducting Pilot Immunization Trials Against East Coast Fever]Report on a Mission to Isolate Theileria parva in Zanzibar and to Assess the Feasability of Conducting Pilot Immunization Trials Against East Coast Fever

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