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Peregrine, A.S.Moloo, S.K.Whitelaw, D.D.[Differences in sensitivity of Kenyan Trypanosoma vivax populations to the prophylactic and therapeutic actions of isometamidium chloride in Boran cattle]Differences in sensitivity of Kenyan Trypanosoma vivax populations to the prophylactic and therapeutic actions of isometamidium chloride in Boran cattle
Zweygarth, E.Kaminsky, R.[Evaluation of an arsenical compound (RM 110, mel Cy, Cymelarsan R) against susceptible drug-resistant Trypanosoma brucei brucei and Trypanosoma brucei evansi]Evaluation of an arsenical compound (RM 110, mel Cy, Cymelarsan R) against susceptible drug-resistant Trypanosoma brucei brucei and Trypanosoma brucei evansi

Mice were immunized with either an isometamidium-human serum albumin (HSA) conjugate or an isometamidium-porcine thyroglobulin conjugate (PTG). Thereafter, monoclonal antibodies (MAbs) IL-A 1001, IL-A 1002, IL-A 1003, 5F7.B7, and 5F7.C9 were generated and selected on the basis that they recognize...


Peregrine, A.S.Eisler, M.C.Katende, J.Flynn, J.N.Gault, E.A.Kinabo, L.D.B.Holmes, P.H.[Generation of monoclonal antibodies to the anti-trypanosomal drug isometamidium]Generation of monoclonal antibodies to the anti-trypanosomal drug isometamidium

Memory T- and B-cell responses to trypanosome antigens were measured in peripheral blood mononuclear cells, spleen and lymph node cells obtained from 4 trypanotolerant N'Dama cattle which had been exposed to 6 experimental infections with Trypanosoma congolense. These cattle were treated with try...


Lutje, V.Taylor, K.A.Boulange, A.F.Authié, E.[Trypanosoma congolense: Tissue distribution of long-term T- and B-cell responses in cattle]Trypanosoma congolense: Tissue distribution of long-term T- and B-cell responses in cattle
Kaminsky, R.Zweygarth, E.[Effect of in vitro cultivation on the stability of resistance of Trypanosoma brucei brucei to diminazene, isometamidium, quinapyramine and mel B]Effect of in vitro cultivation on the stability of resistance of Trypanosoma brucei brucei to diminazene, isometamidium, quinapyramine and mel B
Morzaria, S.P.Irvin, A.D.Wathanga, J.D'Souza, D.Katende, J.M.Young, A.S.Scott, J.R.Gettinby, G.[The effect of East Coast fever immunisation and different acaricidal treatments on the productivity of beef cattle]The effect of East Coast fever immunisation and different acaricidal treatments on the productivity of beef cattle
Peregrine, A.S.Moloo, S.K.Whitelaw, D.D.[Therapeutic and prophylactic activity of isometamidium chloride in Boran cattle against Trypanosoma vivax transmitted by Glossina morsitans centralis]Therapeutic and prophylactic activity of isometamidium chloride in Boran cattle against Trypanosoma vivax transmitted by Glossina morsitans centralis

Six Boran cattle were infected with the drug-resistant Trypanosoma congolense IL 3338. At the first peak of parasitemia different groups of 200 teneral Glossina morsitans centralis were fed once on each animal, just prior to treatment with diminazene aceturate at a dose of 3.5 mg kg-1 body weight...


Diack, A.Moloo, S.K.Peregrine, A.S.[Effect of multiple treatment of cattle with diminazene aceturate on the infectivity and transmissibility of drug-resistant Trypanosoma congolense for Glossina morsitans centralis]Effect of multiple treatment of cattle with diminazene aceturate on the infectivity and transmissibility of drug-resistant Trypanosoma congolense for Glossina morsitans centralis
Hirumi, H.Hirumi, K.Peregrine, A.S.[Axenic culture of Trypanosoma congolense: Application to the detection of sensitivity levels of bloodstream Trypomastigotes to diminazene aceturate, homidium chloride, isometamidium chloride and quinapyramine sulphate]Axenic culture of Trypanosoma congolense: Application to the detection of sensitivity levels of bloodstream Trypomastigotes to diminazene aceturate, homidium chloride, isometamidium chloride and quinapyramine sulphate

Four Trypanosoma (T.) congolense reference clones with known isometamidium sensitivity and 16 T. congolense stocks from cattle in Kenedougou in south-western Burkina Faso, an area with known history of drug resistance, were characterised with the standard mouse test (SMT) and the drug incubatio...


Knoppe, T.N.Bauer, B.McDermott, John J.Peregrine, A.S.Mehlitz, D.Clausen, P.H.[Isometamidium sensitivity of Trypanosoma congolense stocks from cattle in West Africa tested in mice and the drug incubation infectivity test]Isometamidium sensitivity of Trypanosoma congolense stocks from cattle in West Africa tested in mice and the drug incubation infectivity test

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