The main conclusion from the present study is that T. parva sporozoite entry is dependent on a functional host cell actin cytoskeleton and is not driven by the parasite. Treating lymphocytes with cytochalasin D resulted in a dose-dependent reduction in the levels of host cell infection. However, ...
Shaw, M.K.
,
[Theileria parva: Sporozoite entry into bovine lymphocytes is not dependent on the parasite cytoskeleton]
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Theileria parva: Sporozoite entry into bovine lymphocytes is not dependent on the parasite cytoskeleton
Minisatellite tandem repeat elements are well known components of vertebrate genomes, but have not yet been extensively characterized in lower eukaryotes. We describe two unusual. AT-rich minisatellites of the protozoan parasite Theileria parva whose sequences are unrelated to the G/C-rich `chi m...
Bishop, Richard P.
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Morzaria, S.P.
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Gobright, E.I.
,
[Linkage of two distinct AT-rich minisatellites at multiple loci in the genome of Theileria parva]
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Linkage of two distinct AT-rich minisatellites at multiple loci in the genome of Theileria parva
Resistance to nematode parasites can be improved by selection, but efforts to include appropriate traits in commercial livestock breeding programs are only a recent development. Procedures for including resistance in breeding programs are similar to those involving other traits. The steps are des...
Woolaston, R.R.
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Baker, R.L.
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[Prospects of breeding small ruminants for resistance to internal parasites]
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Prospects of breeding small ruminants for resistance to internal parasites
A hybridoma cell line has been previously produced which secretes monoclonal antibodies that neutralize sporozoites of T. parva. Cells from this line were injected i/p into pristane-treated BALB/c mice. During the last 4 days of hybridoma cell growth, mice were given 4 daily i/p injections of a m...
Dobbelaere, D.A.E.
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Spooner, P.R.
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[Production in ascites fluid of biosynthetically labelled monoclonal antibody to Theileria parva sporozoites]
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Production in ascites fluid of biosynthetically labelled monoclonal antibody to Theileria parva sporozoites
Current vaccines for bovine hemoparasites utilize live attenuated organisms or virulent organisms administered concurrently with antiparasitic drugs. Although such vaccines can be effective, for most hemoparasites the mechanisms of acuquired resistance to challenge infection with heterologous par...
Brown, W.C.
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Zhao, S.
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Logan, K.S.
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Grab, D.J.
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Rice-Ficht, A.C.
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[Identification of candidate vaccine antigens of bovine hemoparasites Theileria parva and Babesia bovis by use of helper T cell clones]
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Identification of candidate vaccine antigens of bovine hemoparasites Theileria parva and Babesia bovis by use of helper T cell clones
Davies, A.J.S.
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Hall, J.G.
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Targett, G.A.T.
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Murray, M.
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[The biological significance of the immune response with special reference to parasites and cancer]
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The biological significance of the immune response with special reference to parasites and cancer
Conrad, P.A.
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Baldwin, C.L.
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Brown, W.C.
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Sohanpal, B.K.
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Dolan, T.T.
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Goddeeris, B.M.
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Demartini, J.C.
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Ole-MoiYoi, O.K.
,
[Infection of bovine T cell clones with genotypically distinct Theileria parva parasites and analysis of their cell surface phenotype]
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Infection of bovine T cell clones with genotypically distinct Theileria parva parasites and analysis of their cell surface phenotype