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Journal Article 1998

Autor: Grab, D.J. Naessens, Jan Ole-MoiYoi, O.K.

East coast fever (ECF) is a major tick-borne disease caused by the apicomplexan parasite Theileria parva (1). ECF is an acute leukemia-like disease of cattle that is endemic in eastern, central and souther Africa, where it is responsible for significant mortality and losses in animal production. ...

Enlace original: https://cgspace.cgiar.org/handle/10568/33062

Investigación en Agricultura
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Grab, D.J. ,  Naessens, Jan ,  Ole-MoiYoi, O.K. ,  [Evidence for ADP-ribosylation and G protein in Theileria parva-transformed bovine lymphocytes] ,  Evidence for ADP-ribosylation and G protein in Theileria parva-transformed bovine lymphocytes
Journal Article 1998

Autor: Nene, Vishvanath Morzaria, S.P. Bishop, Richard P.

When compared with other Apicomplexan organisms. Theileria parva has an execptionally small, 10-12 Mbp. genome. There are only 4 chromosomes, each in the Mbp range, and a complete physical map, based on SfiI linking data, is available for each one. A number of genes and cDNAs have been mapped to ...

Enlace original: https://cgspace.cgiar.org/handle/10568/33061

Investigación en Agricultura
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Nene, Vishvanath ,  Morzaria, S.P. ,  Bishop, Richard P. ,  [Organisation and informational content of the Theileria parva genome] ,  Organisation and informational content of the Theileria parva genome
Journal Article 2000

Autor: Hall, R. Boulter, N.R. Brown, C.G.D. Wilkie, G. Kirvar, E. Nene, Vishvanath Musoke, A.J. Glass, E.J. Morzaria, S.P.

Theileria annulata and Theileria parva both poses a major surface antigen on the sporozoite stage of the life-cycle, called SPAG-1 and p67, respectively. In each case, these antigens are vaccine candidates and have been shown to induce a degree of homologous protection in earlier work. These anti...

Enlace original: https://cgspace.cgiar.org/handle/10568/33093

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Hall, R. ,  Boulter, N.R. ,  Brown, C.G.D. ,  Wilkie, G. ,  Kirvar, E. ,  Nene, Vishvanath ,  Musoke, A.J. ,  Glass, E.J. ,  Morzaria, S.P. ,  [Reciprocal cross-protection induced by sporozoite antigens SPAG-1 from Theileria annulata and p67 from Theileria parva] ,  Reciprocal cross-protection induced by sporozoite antigens SPAG-1 from Theileria annulata and p67 from Theileria parva
Journal Article 1998

Autor: Minjauw, B. Otte, M.J. James, A.D. Castro, J.J. de Permin, A. Giulio, Giuseppe di

An outbreak of East Coast fever (ECF) occurred in an experimental herd of Sanga cattle maintained under a traditional rangeland grazing system at Lutale, Central Province of Zambia. Two groups of cattle had been kept under different tick-control regimes for several years prior to the introduction...

Enlace original: https://cgspace.cgiar.org/handle/10568/33110

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Minjauw, B. ,  Otte, M.J. ,  James, A.D. ,  Castro, J.J. de ,  Permin, A. ,  Giulio, Giuseppe di ,  [An outbreak of East Coast Fever in a herd of Sanga cattle in Lutale, Central Province of Zambia] ,  An outbreak of East Coast Fever in a herd of Sanga cattle in Lutale, Central Province of Zambia
Journal Article 2001

Autor: Bishop, Richard P. Geysen, D. Spooner, P.R. Skilton, Robert A. Nene, Vishvanath Dolan, T.T. Morzaria, S.P.

The 'Muguga cocktail' which is composed of three Theileria parva stocks Muguga. Kiambu 5 and Serengeti-transformed has been used extensively for live vaccination against East Coast fever in cattle in eastern, central and southern Africa. Herein we describe the molecular characterization of the T....

Enlace original: https://cgspace.cgiar.org/handle/10568/33253

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Bishop, Richard P. ,  Geysen, D. ,  Spooner, P.R. ,  Skilton, Robert A. ,  Nene, Vishvanath ,  Dolan, T.T. ,  Morzaria, S.P. ,  [Molecular and immunological characterisation of Theileria parva stocks which are components of the Muguga cocktail used for vaccination against East Coast fever in cattle] ,  Molecular and immunological characterisation of Theileria parva stocks which are components of the Muguga cocktail used for vaccination against East Coast fever in cattle
Journal Article 1998

Autor: Honda, Y. Matsubara, Y. Morzaria, S.P. McKeever, Declan J.

Theileria parva is the causal agent of East Coast fever (ECF), a fatal disease of cattle characterized by pyrexia, transient lymphadenopathy and panleukopenia. We have evaluated monoclonal antibodies (mAb) against three distinct antigens (p67, PIM and p32) of the parasite as immunohistological re...

Enlace original: https://cgspace.cgiar.org/handle/10568/33247

Investigación en Agricultura
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Honda, Y. ,  Matsubara, Y. ,  Morzaria, S.P. ,  McKeever, Declan J. ,  [Immunohistochemical detection of parasite antigens in Theileria parva-infected bovine lymphocytes] ,  Immunohistochemical detection of parasite antigens in Theileria parva-infected bovine lymphocytes
Journal Article 1999

Autor: McKeever, Declan J. Taracha, E.L.N. Morrison, W. Ivan Musoke, A.J. Morzaria, S.P.

Theileria parva is an intracellular sporozoan parasite that infects and transforms bovine lymphocytes, causing a severe lymphoproliferative disease known as East Coast fever in eastern, central and southern Africa. In this article, Declan McKeever and colleagues summarize the current understandin...

Enlace original: https://cgspace.cgiar.org/handle/10568/33104

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McKeever, Declan J. ,  Taracha, E.L.N. ,  Morrison, W. Ivan ,  Musoke, A.J. ,  Morzaria, S.P. ,  [Protective immune mechanisms against Theileria parva: Evolution of vaccine development strategies] ,  Protective immune mechanisms against Theileria parva: Evolution of vaccine development strategies
Journal Article 2003

Autor: Bishop, Richard P. Nene, Vishvanath Staeyert, J. Rowlands, G.J. Nyanjui, J. Osaso, J. Morzaria, S.P. Musoke, A.J.

Full-length recombinant versions of p67, the 709 amino acid major surface protein of Theileria parva sporozoites, induce immunity to East Coast fever (ECF) in cattle. We show that a soluble Escherichia coli recombinant version of p67 (p67635), in which a prokaryotic signal peptide replaces the e...

Enlace original: https://cgspace.cgiar.org/handle/10568/33215

Investigación en Agricultura
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Bishop, Richard P. ,  Nene, Vishvanath ,  Staeyert, J. ,  Rowlands, G.J. ,  Nyanjui, J. ,  Osaso, J. ,  Morzaria, S.P. ,  Musoke, A.J. ,  [Immunity to East Coast fever in cattle induced by a polypeptide fragment of the major surface coat protein of Theileria parva sporozoites] ,  Immunity to East Coast fever in cattle induced by a polypeptide fragment of the major surface coat protein of Theileria parva sporozoites
Journal Article 2005

Autor: Kaba, S.A. Musoke, A.J. Schaap, D. Schetters, T. Rowlands, G.J. Vermeulen, A.N. Nene, Vishvanath Vlak, J.M. Oers, M.M. van

Two novel baculovirus-derived recombinant Theileria parva p67 constructs were tested for their vaccine potential against East Coast fever. Boran calves were immunized with a his-GFP-p67 fusion protein (GFP:p67DeltaSS) or with GP64:p67C, a protein fusion between a C-terminal domain of p67 and th...

Enlace original: https://cgspace.cgiar.org/handle/10568/33217

Investigación en Agricultura
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Kaba, S.A. ,  Musoke, A.J. ,  Schaap, D. ,  Schetters, T. ,  Rowlands, G.J. ,  Vermeulen, A.N. ,  Nene, Vishvanath ,  Vlak, J.M. ,  Oers, M.M. van ,  [Novel baculovirus-derived p67 subunit vaccines efficacious against East Coast fever in cattle] ,  Novel baculovirus-derived p67 subunit vaccines efficacious against East Coast fever in cattle
Journal Article 1999

Autor: Minjauw, B. Rushton, Jonathan James, A.D. Upton, M.

Five different East Coast fever (ECF)-control strategies (involving ECF immunisation by the infection-and-treatment method) were tested in groups of traditionally managed Sanga cattle in the Central Province of Zambia over a period of 2.5 years. Two groups were under intensive tick control (weekl...

Enlace original: https://cgspace.cgiar.org/handle/10568/33111

Investigación en Agricultura
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Minjauw, B. ,  Rushton, Jonathan ,  James, A.D. ,  Upton, M. ,  [Financial analysis of East Coast Fever control strategies in traditionally managed Sanga cattle in Central Province of Zambia] ,  Financial analysis of East Coast Fever control strategies in traditionally managed Sanga cattle in Central Province of Zambia

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