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Ellis, J.A.Fish, W.R.Sileghem, M.R.McOdimba, F.A.[A calorimetric assay for trypanosome viability and metabolic function]A calorimetric assay for trypanosome viability and metabolic function

A visually read dot-enzyme linked immunosorbent asay (dot-ELISA) developed for the detection of trypanosomes in tsetse flies (Glossina spp.) was evaluated in the laboratory and under field conditions. In the evaluation, the fly dissection method was used as a standard technique and compared to th...


Ouma, J.O.Masake, R.A.Masiga, Daniel K.Moloo, S.K.Njuguna, J.T.Ndung'u, J.M.[Comparative sensitivity of dot-ELISA, PCR and dissection method for the detection of trypanosome infections in tsetse flies (Diptera: Glossinidae)]Comparative sensitivity of dot-ELISA, PCR and dissection method for the detection of trypanosome infections in tsetse flies (Diptera: Glossinidae)

The frequency of trypanosomes resistant to diminazene aceturate at a dose of 26 mg/kg of bwt was investigated for populations of Trypanosoma congolense IL 3274 which reappeared in infected mice after intraperitoneal treatment with diminazene aceturate at the same dosage. At inoculum sizes of 102,...


Mamman, M.Gettinby, N.B.Murphy, N.B.Kemei, S.Peregrine, A.S.[Frequency of diminazene - resistant trypanosomes in populations of Trypanosoma congolense arising in infected animals following treatment with diminazene aceturate]Frequency of diminazene - resistant trypanosomes in populations of Trypanosoma congolense arising in infected animals following treatment with diminazene aceturate

Five adult Boran cattle (Bos indicus), infected with a clone of Trypanosoma congolense IL13-E3 three years earlier and treated, were re-challenged with the same clone. Changes in the peripheral blood were monitored twice weekly, and events in the bone marrow (BM) were assessed by weekly biopsies ...


Anosa, V.O.Logan-Henfrey, L.L.Wells, C.W.[The haematology of Trypanosoma congolense infection in cattle. I. Sequential cytomorphological changes in the blood and bone marrow of Boran cattle]The haematology of Trypanosoma congolense infection in cattle. I. Sequential cytomorphological changes in the blood and bone marrow of Boran cattle

Sequential biopsies of sternal bone marrow (BM) of three trypanosusceptible Boran and three trypanotolerant N'Dama cattle were examined by light and transmission electron microscopy before and up to 112 days postinfection (DPI) with Trypanosoma congolense. Before infection, the percentage of cell...


Anosa, V.O.Logan-Henfrey, L.L.Wells, C.W.[The role of the bone marrow in bovine trypanotolerance. II. Macrophage function in Trypanosoma congolense - infected cattle]The role of the bone marrow in bovine trypanotolerance. II. Macrophage function in Trypanosoma congolense - infected cattle

Macrophages (Mo) in smears and sections of sternal bone marrow (BM) derived by weekly sequential biopsies from five adult Boran cattle re-challenged with Trypanosoma congolense were studied by light and transmission electron microscopy (TEM). Cells of the mononuclear phagocyte system including mo...


Anosa, V.O.Logan-Henfrey, L.L.Wells, C.W.[The haematology of Trypanosoma congolense infection in cattle. II. Macrophage structure and function in the bone marrow of Boran cattle]The haematology of Trypanosoma congolense infection in cattle. II. Macrophage structure and function in the bone marrow of Boran cattle

Isometamidium chloride has remained a very important prophylactic and therapeutic drug against trypanosomosis in cattle since its introduction into the market in the 1950s with, unfortunately, a concomitant development of resistance in trypanosomosis endemic areas. Amplified Fragment Length Polym...


Delespaux, V.Geysen, D.Majiwa, P.A.O.Geerts, S.[Identification of a genetic marker for isometamidium chloride resistance in Trypanosoma congolense]Identification of a genetic marker for isometamidium chloride resistance in Trypanosoma congolense
Hirumi, H.Hirumi, K.[In vitro cultivation of Trypanosoma congolense bloodstream forms in the absence of feeder cell layers]In vitro cultivation of Trypanosoma congolense bloodstream forms in the absence of feeder cell layers
Peregrine, A.S.Knowles, G.Ibitayo, A.I.Scott, J.R.Moloo, S.K.Murphy, N.B.[Variation in resistance to isometamidium chloride and diminazene aceturate by clones derived from a stock of Trypanosoma congolense]Variation in resistance to isometamidium chloride and diminazene aceturate by clones derived from a stock of Trypanosoma congolense
Murray, M.Hirumi, H.Moloo, S.K.[Suppression of Trypanosoma congolense, Trypanosoma vivax and Trypanosoma brucei infection rates in tsetse flies maintained on goats immunised with uncoated forms of trypanosomes grown in vitro]Suppression of Trypanosoma congolense, Trypanosoma vivax and Trypanosoma brucei infection rates in tsetse flies maintained on goats immunised with uncoated forms of trypanosomes grown in vitro

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