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An average of 840 East African Zebu cattle from nine herds in the Ghibe Valley, southwest Ethiopia were monitored from 1986 to 1990. Each month blood samples were collected from analysis of packed red cell volume and detection of trypanosomes. Animals were found to be parasitaemic and with a PCV ...


Rowlands, G.J.Mulatu, W.Authie, A.D'Ieteren, G.D.M.Leak, S.G.A.Nagda, S.M.Peregrine, A.S.[Epidemiology of bovine trypanosomiasis in the Ghibe Valley, southwest Ethiopia. 2. Factors associated with variations in trypanosome prevalence, incidence of new infections and prevalence of recurrent infections]Epidemiology of bovine trypanosomiasis in the Ghibe Valley, southwest Ethiopia. 2. Factors associated with variations in trypanosome prevalence, incidence of new infections and prevalence of recurrent infections

The sensitivity of seven populations of T. congolense to the salts of three trypanocides, diminazene, isometamidium and homidium, were determined in vitro using in vitro-derived metacyclic trypanosomes. The trypanosomes were incubated at 35 degree centigrade for 48 hours with various drug concent...


Gray, M.A.Peregrine, A.S.[An in vitro assay for drug sensitivity of Trypanosoma congolense using in vitro-derived metacyclic trypanosomes]An in vitro assay for drug sensitivity of Trypanosoma congolense using in vitro-derived metacyclic trypanosomes

Affognon, Hippolyte D.Matsaert, H.Puskur, RanjithaRandolph, Thomas F.[Disseminating research results on trypanocide resistance in West Africa: a method for identifying effective pathways]Disseminating research results on trypanocide resistance in West Africa: a method for identifying effective pathways

A Trypanosoma brucei brucei DNA repeat sequence termed NlaIII repeat (NR) was originally isolated from a multidrug-resistant field isolate CP547 [Jamnadass, R., 1995. Identification and characterisation of an extrachromosomal element from a multidrug-resistant isolate of T. brucei brucei, Ph.D. t...


Jamnadass, Ramni H.Pelle, RogerPandit, P.Ricard, B.Murphy, N.B.[Trypanosoma brucei: Composition, organisation, plasticity, and differential transcription of NlaIII repeat elements in drug-resistant and sensitive isolates]Trypanosoma brucei: Composition, organisation, plasticity, and differential transcription of NlaIII repeat elements in drug-resistant and sensitive isolates

Cattle from 50 farms in Mukono County, Uganda, were monitored for trypanosomes every second month over an 18-month period (1995–1996) by mini-anion exchange chromatography and haematocrit centrifugation techniques. Eighteen trypanosome isolates collected from cattle during this period were charac...


Olila, D.McDermott, John J.Eisler, M.C.Mitema, E.S.Patzelt, R.J.Clausen, P.H.Poetzsch, C.J.Zessin, K.H.Mehlitz, D.Peregrine, A.S.[Drug sensitivity of trypanosome populations from cattle in a peri-urban dairy production system in Uganda]Drug sensitivity of trypanosome populations from cattle in a peri-urban dairy production system in Uganda

Isometamidium chloride has remained a very important prophylactic and therapeutic drug against trypanosomosis in cattle since its introduction into the market in the 1950s with, unfortunately, a concomitant development of resistance in trypanosomosis endemic areas. Amplified Fragment Length Polym...


Delespaux, V.Geysen, D.Majiwa, P.A.O.Geerts, S.[Identification of a genetic marker for isometamidium chloride resistance in Trypanosoma congolense]Identification of a genetic marker for isometamidium chloride resistance in Trypanosoma congolense

International Laboratory for Research on Animal Diseases[ILRAD Reports. Volume 10. Number 4. October 1992]ILRAD Reports. Volume 10. Number 4. October 1992

International Laboratory for Research on Animal Diseases[ILRAD Reports. Volume 8. Number 2. April 1990]ILRAD Reports. Volume 8. Number 2. April 1990
Autor: Hood, G.M.

This chapter reviews the current status of anthelmintic resistance in Southeast Asia, and examines the implications for smallholders, for whom anthelmintics offer one key to the control of parasitism and the development of enterprises based on small ruminants. Alternatives to the use of anthelmin...


Hood, G.M.[Anthelmintic resistance in small ruminant parasites: Implications for smallholders in Southeast Asia]Anthelmintic resistance in small ruminant parasites: Implications for smallholders in Southeast Asia

International Laboratory for Research on Animal Diseases[How trypanosomes tolerate drugs that once killed them]How trypanosomes tolerate drugs that once killed them

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