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Barbet, A.F.Musoke, A.J.Mpimbaza, G.W.N.Rovis, L.[Isolation of a variant antigen fragment containing cross-reacting determinants from Trypanosoma brucei]Isolation of a variant antigen fragment containing cross-reacting determinants from Trypanosoma brucei

Various parasitic protozoa of the family Trypanosomatidae such as Crithidia spp. [1]; Trypanosoma cruzi [2]; Leishmania donovani [3] and salivarian trypanosomes [4-8] have been shown to contain acid phosphatase activity (EC.3.1.3.2, orthophosphoric-monoester phosphohydrolase activity). Acid phosp...


Grab, D.J.Webster, P.Verjee, Y.Lonsdale-Eccles, J.[Golgi-associated phosphohydrolases in Trypanosoma brucei brucei]Golgi-associated phosphohydrolases in Trypanosoma brucei brucei
Kimmel, B.E.Ole-MoiYoi, O.K.Young, J.R.[Ingi, a 5.2-Kb dispersed sequence element from Trypanosoma brucei that carries half of a smaller mobile element at either end and has homology with mammalian lines]Ingi, a 5.2-Kb dispersed sequence element from Trypanosoma brucei that carries half of a smaller mobile element at either end and has homology with mammalian lines
Alexandre, S.Guyaux, M.Murphy, N.B.Coquelet, H.Pays, A.Steinert, M.Pays, E.[Putative genes of a variant-specific antigen gene transcription unit in Trypanosoma brucei]Putative genes of a variant-specific antigen gene transcription unit in Trypanosoma brucei

The membrane-associated form of the variable surface glycoprotein (mfVSG) from African trypanosomes is a potent macrophage activator capable of inducing production of tumor necrosis factor z (TNFalfa) in both bovine and murine models. Using a bovine model. we have re-investigated the hypothesis t...


Sileghem, M.R.Saya, R.Grab, D.J.Naessens, Jan[An accessory role for the diacylglycerol moiety of variable surface glycoprotein of African trypanosomes in the simulation of bovine monocytes]An accessory role for the diacylglycerol moiety of variable surface glycoprotein of African trypanosomes in the simulation of bovine monocytes

Susceptibility of African buffalo, eland, waterbuck, N'Dama and Boran cattle to sequential Glossina morsitans centralis-transmitted infections of Trypanosoma congolense, T. brucei brucei and T. vivax was compared, and their possible role as reservoirs of these parasites for G. moristans centralis...


Moloo, S.K.Orinda, G.O.Sabwa, C.L.Minja, S.H.Masake, R.A.[Study on the sequential tsetse-transmitted Trypanosoma congolense, T. brucei brucei and T. vivax infections to African buffalo, eland, waterbuck, N'Dama and Boran cattle]Study on the sequential tsetse-transmitted Trypanosoma congolense, T. brucei brucei and T. vivax infections to African buffalo, eland, waterbuck, N'Dama and Boran cattle

Under most circumstances, certain breeds of domestic ruminants show a remarkable resistance to the effects of African trypanosomiasis: they can tolerate the presence of parasites while apparently controlling levels of parasitaemia and, crucially, not showing the the severe anaemia and production ...


Kemp, Stephen J.Teale, A.J.[Genetic basis of trypanotolerance in cattle and mice]Genetic basis of trypanotolerance in cattle and mice
Autor: Parkin, D.W.

Trypanosomes have no de novo purine biosynthesis and thus depend upon salvage pathways to obtain purines for their metabolic pathways and for the biosynthesis of nucleic acids. An inosine-adenosine-guanosine preferring nucleoside hydrolase (IAG-nucleoside hydrolase) from the African trypanosome T...


Parkin, D.W.[Purine-specific nucleoside N-ribohydrolase from Trypanosoma brucei brucei. Purification, specificity, and kinetic mechanism]Purine-specific nucleoside N-ribohydrolase from Trypanosoma brucei brucei. Purification, specificity, and kinetic mechanism
Webster, P.Russo, D.C.W.Black, S.J.[The interaction of Trypanosoma brucei with antibodies to variant surface glycoproteins]The interaction of Trypanosoma brucei with antibodies to variant surface glycoproteins
Webster, P.Grab, D.J.[Intracellular localization of variant surface glycoprotein and transferrin-gold in Trypanosoma brucei]Intracellular localization of variant surface glycoprotein and transferrin-gold in Trypanosoma brucei

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