Methods for determining the efficacy of animal health interventions involving vector-borne diseases when the intervention attempts to control the vector itself are described. There are a number of possibilities. For example, a before/after study can be undertaken when data collected following the...
Rowlands, G.J.
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[Statistical issues in the design and analysis of animal health interventions for vector-borne disease]
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Statistical issues in the design and analysis of animal health interventions for vector-borne disease
Tsetse-transmitted trypanosomosis affects cattle production over approximately 10 million km2 of Africa. In these areas, trypanocidal drugs, both prophylactic and curative, are the most widely used methods of trypanosomosis control. However, resistance of trypanosomes to the 3 trypanocidal drugs ...
McDermott, John J.
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Coleman, P.G.
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Eisler, M.C.
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Peregrine, A.S.
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[The effects of resistance to trypanocidal drugs on trypanosome transmission]
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The effects of resistance to trypanocidal drugs on trypanosome transmission
Host ability to control the Development of trypanosomes is a major component of trypanotolerance. However, practical indicators of the parasite control capability have still to be identified as they rely on the availability of more precise diagnostic techniques that could be carried out at the fa...
Wissocq, N.M.
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D'Ieteren, G.D.M.
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Trail, J.C.M.
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Masake, R.
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Nantulya, V.M.
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Monsengo, B.
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[Trypanosome antigen test to characterise infection status in N'Dama cattle]
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Trypanosome antigen test to characterise infection status in N'Dama cattle
In this study, the efficacies of three trypanocidal drugs, diminazene aceturate, isometamidium chloride and homidium bromide, were evaluated in four representative areas of Cote d'Ivoire with different production systems, degree of integration of different trypanosomosis control approaches and de...
D'Ieteren, G.D.M.
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Coulibaly, L.
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Atse, P.A.
,
Hecker, P.A.
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Krebs, H.A.
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Rowlands, G.J.
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Leak, S.G.A.
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Nagda, S.M.
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[Trypanocidal drug resistance in West Africa]
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Trypanocidal drug resistance in West Africa
The identification and tracking of sub-populations through time and space are critical to fully understanding the epidemiology of parasitic diseases. However, very little is known about the structure, distribution and dynamics of trypanosome populations in the field. Most laboratory studies that ...
Coleman, P.G.
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McDermott, John J.
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[Trypanosome population biology - an approach to support the control of drug resistance and integrated trypanosomosis control]
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Trypanosome population biology - an approach to support the control of drug resistance and integrated trypanosomosis control
Reports the feeding preferences of Glossina species at sites of the African Trypanotolerant Livestock Network. Estimates tsetse challenge and relates the results with trypanosome prevalence in cattle. Examines the relationship between tsetse challenge using linear regression analysis. Also examin...
Leak, S.G.A.
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Colardelle, C.
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Coulibaly, L.
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D'Ieteren, G.D.M.
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Dumont, P.
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Feron, A.
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Hecker, P.
,
Jeannin, P.
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Maloo, S.H.
,
Minengu, M.
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Minja, S.
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Mulatu, W.
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Mulungo, M.
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Nankodaba, G.
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Ngamuna, S.
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Ordner, G.
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Sauveroche, B.
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Schuetterle, A.
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Tikubet, G.
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Touré, M.
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Trail, J.C.M.
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Tsotsi, E.
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Yangari, G.
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[Tsetse feeding habits and tsetse challenge at sites of the African Trypanotolerant Livestock Network]
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Tsetse feeding habits and tsetse challenge at sites of the African Trypanotolerant Livestock Network
International Laboratory for Research on Animal Diseases
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[Clearance of antibody-VSG complexes by trypanosomes]
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Clearance of antibody-VSG complexes by trypanosomes
Earlier research had provided clear indications of an ability of N'Dama cattle to acquire, over time, some control of the Development of parasitaemia following a T. vivax infection but not apparently, following a T. congolense infection. The objective of this study is to further assess the import...
Wissocq, N.M.
,
D'Ieteren, G.D.M.
,
Trail, J.C.M.
,
Monsengo, B.
,
[Ability to acquire resistance to trypanosome infections and growth of N'Dama cattle]
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Ability to acquire resistance to trypanosome infections and growth of N'Dama cattle
The extent and significance of trypanocidal drug resistance was investigated in priority areas of three East and Southern African Countries under a project. The project was built on the results of two previous projects. Existing methods currently available for the demonstration of drug-resistance...
Eisler, M.C.
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Ndung'u, J.M.
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Murilla, G.
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Mdachi, R.M.
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Mbwambo, H.
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Sinyangwe, L.
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Machila, N.
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Delespaux, V.
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Geerts, S.
,
Brandt, J.
,
Peregrine, A.S.
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McDermott, John J.
,
Holmes, P.H.
,
[Area-wide appraisal of drug resistance in trypanosomes infecting cattle in East and Southern Africa]
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Area-wide appraisal of drug resistance in trypanosomes infecting cattle in East and Southern Africa
Advances in biotechnological techniques are driven by the needs of the human populations. The new techniques in biotechnology have been developed as a consequence of the integrated use of microbiology, biochemistry and chemical engineering. Some of these technologies are being employed in the der...
Masake, R.A.
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Musoke, A.J.
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Ole-MoiYoi, O.K.
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[Application of biotechnology in disease diagnosis and vaccine Development]
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Application of biotechnology in disease diagnosis and vaccine Development