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Among arthropods, ticks lead as vectors of animal diseases and rank second to mosquitoes in transmitting human pathogens. Cyclin-dependent kinases (CDK) participate in cell cycle control in eukaryotes. CDKs are serine/threonine protein kinases and these catalytic subunits are activated or inactiv...
The Global Forum on Agricultural Research's (GFAR) mission is to mobilize the world scientific community in their effort to alleviate poverty increase food security and promote the sustainable use of natural resources. GFAR plays a role of facilitator between stakeholders, in particular scientist...
The current Infection and Treatment Method of vaccination against East Coast fever comprises an inoculation of live Theileria parva sporozoites and simultaneous administration of oxytetracycline. Immunization with a combination of parasite types has been shown to provide broader protection than i...
Development of improved vaccine and diagnostic-based disease control strategies has benefited considerably from advances in biotechnology, particularly those relating to recombinant DNA technology. Efficiency of the vaccine development process has been increased at all levels, from the analysis o...
In part I of this review of the prospects of vaccination against African trypanosomiasis, contained in the previous issue of World Animal Review, the constraints in developing a vaccine were discussed and current knowledge on the molecular biology of the trypanosome and on antigenic variation wit...
Heterologous priming-boosting vaccination regimens involving priming with plasmid DNA antigen constructs and inoculating (boosting) with the same recombinant antigen expressed in replication-attenuated poxviruses have recently been demonstrated to induce immunity, based on CD4(+)- and CD8(+)-T-c...
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