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Approximately 320 East African Zebu cows over 36 months of age were monitored monthly from 1986 to 1992 in nine village herds in an area of high trypanosomiasis risk in southwest Ethiopia where there was resistance to all available trypanocidal drugs. Cows were individually treated with diminazen...


Rowlands, G.J.Woudyalew MulatuNagda, S.M.D'Ieteren, G.D.M.[Variations in packed red cell volume and trypanosome prevalence and relationships with reproductive traits in East African Zebu cows exposed to drug-resistant trypanosomes]Variations in packed red cell volume and trypanosome prevalence and relationships with reproductive traits in East African Zebu cows exposed to drug-resistant trypanosomes

The sensitivity of seven populations of T. congolense to the salts of three trypanocides, diminazene, isometamidium and homidium, were determined in vitro using in vitro-derived metacyclic trypanosomes. The trypanosomes were incubated at 35 degree centigrade for 48 hours with various drug concent...


Gray, M.A.Peregrine, A.S.[An in vitro assay for drug sensitivity of Trypanosoma congolense using in vitro-derived metacyclic trypanosomes]An in vitro assay for drug sensitivity of Trypanosoma congolense using in vitro-derived metacyclic trypanosomes

A modified NC membrane-based dot-ELISA was used to detect and differentiate between Trypanosoma brucei, T. congolense and T. simiae procyclics in the midguts of experimentally infected tsetse flies. The modification of the assay consisted of (a) the lysis of T. congolense or T. simiae in NC membr...


Bosompem, K.M.Moloo, S.K.Assoku, R.K.G.Nantulya, V.M.[Detection and differentiation between trypanosome species in experimentally infected tsetse flies (Glossina spp.) using dot-ELISA]Detection and differentiation between trypanosome species in experimentally infected tsetse flies (Glossina spp.) using dot-ELISA

Infection of livestock with African trypanosomes leads to haematological changes such as anaemia and pancytopenia and to immune defects, including suppression of T-cell responsiveness and an excessive increase in the CD5+ B-cell population in blood and spleen. It has been shown that certain breed...


Mertens, B.Gaidulis, L.Mwangi, S.Suliman, H.Taylor, K.A.[Development of bovine-specific cytokine reagents at ILRAD]Development of bovine-specific cytokine reagents at ILRAD
Codjia, V.[Characterisation of Trypanosome isolates collected from cattle in Ghibe, Ethiopia.]Characterisation of Trypanosome isolates collected from cattle in Ghibe, Ethiopia.
Autor: Kang'a, S.

Tsetse-transmitted trypanosomosis poses severe constraints to livestock productivity in sub-Saharan Africa, affecting large areas of the continent that hold the greatest potential for agricultural development. Greater exploitation of the genetic resistance to trypanosomosis (trypananotolerance) t...


Kang'a, S.[Development and application of genetic markers linked to A QTL controlling resistance to trypanosomosis on bovine chromosome 7.]Development and application of genetic markers linked to A QTL controlling resistance to trypanosomosis on bovine chromosome 7.

The current control strategies for tsetse-transmitted trypanosomosis in cattle (trypanocidal drugs tsetse control and trypanotolerant cattle) are briefly reviewed and their adoption rates in different geographic regions of sub-Saharan Africa are presented. The impact of these control strategies a...


McDermott, John J.Coleman, P.G.[Comparing apples and oranges - model-based assessment of different tsetse-transmitted trypanosomosis control strategies]Comparing apples and oranges - model-based assessment of different tsetse-transmitted trypanosomosis control strategies
Kaminsky, R.Zweygarth, E.Gumm, I.D.Chuma, Francis[In vitro-assays zur bestimmung der medikamenten-resistenz bei afrikanischen trypanosomen (Determination of African Trypanosoma drug resistance by means of in vitro assays)]In vitro-assays zur bestimmung der medikamenten-resistenz bei afrikanischen trypanosomen (Determination of African Trypanosoma drug resistance by means of in vitro assays)

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