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Los fibroblastos cardiacos (CF) son células claves en la mantención de la matriz extracelular (MEC), homeostasis del tejido cardiaco y también en la reparación tisular a través de la diferenciación a miofibroblasto (MFC). Además, los FC cumplen un rol centinela, siendo capaces de responder...

Cardiac fibroblasts (CF) are a key cell for maintaining extracellular matrix (ECM), protein homeostasis in heart tissue and also for cardiac repair through CF-to cardiac myofibroblast (CMF) differentiation. Moreover, CF play a sentinel role in response to mechanical and chemical stimuli by releas...

Breast cancer is the leading cause of cancer-related deaths in women. Although the incidence of this disease has decreased thanks to the implementation of screening mammograms and application of adjuvant therapies, this decrease does not seem to be enough, since the development of metastasis is s...

The aim of this project has narrowed around cortico-cochlear modulations under selective attention to visual stimuli. Visual and auditory tasks were performed in alternating fashion by subjects whose electroencephalogram (EEG, 32 channels) and otoacoustic emmisions were recorded continuously and ...

En nuestra sociedad moderna, la luz artificial y la reestructuración de los horarios de trabajo nos han apartado progresivamente del ciclo natural de luz y oscuridad, provocando la alteración de los ritmos biológicos que poseen una oscilación cercana a un día (circadianos). Numerosos estudios dem...

In our modern society, artificial light and the re-structuring the work times has progressively detached us from natural cycle of light and dark, resulting in disruption of the biological rhythms that have an oscillation close to a day (circadian rhythms). A growing body of evidence demonstrate t...

Other than surgery, radiotherapy is the standard treatment for colorectal cancer (CRC). Conventional protocol consists of administering high doses (≥ 2 Gy) of ionizing radiation (IR), which is associated with several side effects. Intriguingly, cell death induction after exposure to low-dose IR (...

Luego de la cirugía, la radioterapia es el tratamiento estándar para el cáncer colorrectal (CCR). Los protocolos convencionales consisten en la administración de dosis altas de radiación ionizante (≥ 2 Gy), la cual ha sido asociada a distintos efectos adversos. Interesantemente, se ha report...