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El cáncer de vesícula biliar (CVB) corresponde a la principal causa de muerte en mujeres mayores de 65 años en Chile. Su sobrevida a 5 años en estadíos avanzados es menor al 10%. Nuestro laboratorio ha logrado inducir la maduración de células dendríticas (DC) con un lisado celular alogénico condi...

Gallbladder cancer is the leading cause of death in women over 65 years in Chile. Five-year survival rate is less than 10%. Previous results from our lab confirm the possibility to induce the maturation of DCs using a heat shocked conditioned cell lysate. 60% of treated patients showed a Delayed ...

Actualmente, el trasplante de órganos es considerado como un tratamiento de elección en pacientes que presentan falla permanente de un órgano. Para evitar el rechazo del órgano trasplantado por parte del organismo receptor se utiliza la inmunosupresión farmacológica. La utilización de estas droga...

Organ transplantation is considered a treatment of choice in patients who have permanent organ failure. To avoid rejection of the transplanted organ by the recipient organism, pharmacological immunosuppression is used. The use of these drugs in certain cases is not enough to prevent the reject...

Aumentos de Angiotensina II (AngII) plasmática causan Hipertensión Arterial (HTA), inflamación y daño de tejidos blanco. Estudios recientes indican que el sistema inmune participa en la generación del aumento de presión arterial (PA) en respuesta AngII. El suministro de fármacos inmunosupresores ...

High Angiotensin II (AngII) plasma levels cause Hypertension (HBP), inflammation and target tissues damage. Recent studies indicate that the immune system participates in the generation of increased blood pressure (BP) in response to AngII. The administration of immunosuppressive drugs that decre...

Non-alcoholic fatty liver disease (NAFLD), defined as fat accumulation >5% in hepatocytes, may progress to fibrosis or cirrhosis later in life. NAFLD prevalence in adolescents has increased significantly in direct relation with obesity prevalence. Objective: To identify anthropometric variables d...

Introduction There is a proved association of mal nutrition in all its forms (obesity, undernutrition and other dietary risks) and climate change (Patterson et al., 2019). In the last report of the Lancet Commissions this concept is defined as “Syndemic” due to the synergy that these three main i...