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Abstract Background Poor prognosis in gallbladder cancer is due to late presentation of the disease, lack of reliable biomarkers for early diagnosis and limited targeted therapies. Early diagnostic markers and novel therapeutic targets can significan...


Subbannayya, Tejaswini.García Cañete, Patricia.Roa, Juan C.Leal Rojas, Pamela.Barbhuiya, Mustafa A.Raja, Remya.Renuse, Santosh.Sathe, Gajanan.Pinto, Sneha M.Syed, Nazia.[Macrophage migration inhibitory factor - a therapeutic target in gallbladder cancer]Macrophage migration inhibitory factor - a therapeutic target in gallbladder cancer

Orellana, Renan.Kato Cardemil, Sumie Rode.Erices, Rafaela.Bravo, María L.González Hevia, Pamela Andrea.Oliva, Bárbara.Cubillos Alfaro, Sofía María Jesús.Valdivia Román, Andrés Felipe.Brañes, Jorge.Cuello F., Mauricio.Ibañez, Carolina.Barriga, María I.Bravo, Erasmo.Alonso, Catalina.Bustamente, Eva.Castellon, Enrique.Hidalgo, Patricia.Trigo, Cesar.Panes Becerra, Olga Teresa.Pereira Garcés, Jaime Ignacio.Mezzano, Diego.Owen, Gareth Ivor.[Platelets enhance tissue factor protein and metastasis initiating cell markers, and act as chemoattractants increasing the migration of ovarian cancer cells.]Platelets enhance tissue factor protein and metastasis initiating cell markers, and act as chemoattractants increasing the migration of ovarian cancer cells.

Dinka MandakovicClaudia RojasJonathan MaldonadoMauricio LatorreDante TravisanyErwan DelageAudrey Bihou�eFrancisca P. D�azClaudio LatorreSergio A. Navarreteet al.[Structure and co-occurrence patterns in microbial communities under acute environmental stress reveal ecological factors fostering resilience]Structure and co-occurrence patterns in microbial communities under acute environmental stress reveal ecological factors fostering resilience

Abstract Background Caveolin-1 (CAV1) has been implicated both in tumor suppression and progression, whereby the specific role appears to be context dependent. Endometrial cancer is one of the most common malignancies of the female genital tract; how...


Diaz Valdivia, Natalia.Owen, Gareth Ivor.Bravo, Denisse.Huerta, Hernán.Henriquez, Soledad.Gabler, Fernando.Vega, Margarita.Romero, Carmen.Calderon, Claudia.Leyton, Lisette.Quest, Andrew F. G.[Enhanced caveolin-1 expression increases migration, anchorage-independent growth and invasion of endometrial adenocarcinoma cells]Enhanced caveolin-1 expression increases migration, anchorage-independent growth and invasion of endometrial adenocarcinoma cells

Abstract Background Hard consistency, developed under the influence of tumor cell factors, is a characteristic feature of a breast tumor. Activation of resident fibroblasts leading to a myofibroblast phenotype is the principal feature that orchestrat...


Arancibia, Rodrigo.Smith, Patricio C.Tobar, Nicolás.Toyos, Marcela.Urra, Carla.Méndez, Nicolás.Martínez, Jorge.[c-Jun N terminal kinase modulates NOX-4 derived ROS production and myofibroblasts differentiation in human breast stromal cells]c-Jun N terminal kinase modulates NOX-4 derived ROS production and myofibroblasts differentiation in human breast stromal cells

Abstract Background Human papillomavirus (HPV) is the etiological factor for cervical cancer and its precursor lesions. The characterization of HPV genotypes in preneoplastic lesions and cervical cancer could establishes t...


Roa, Juan C.Brebi, Priscilla.Ili, Carmen G.Andana, Alejandra.Menzel, Doris.Lopez, Jaime.Guzman, Pablo.Melo, Angelica.Buchegger, Kurt.[Frequency of Human papillomavirus in women attending cervical cancer screening program in Chile]Frequency of Human papillomavirus in women attending cervical cancer screening program in Chile

P. I. MorenoI. VilanovaR. Villa-Mart�nezR. B. DunbarD. A. MucciaroneM. R. KaplanR. D. GarreaudM. RojasC. M. MoyR. De Pol-Holz & F. Lambert[Onset and Evolution of Southern Annular Mode-Like Changes at Centennial Timescale]Onset and Evolution of Southern Annular Mode-Like Changes at Centennial Timescale

Abstract Background In Chile, more than 500 women die every year from cervical cancer, and a majority of Chilean women are not up-to-date with their Papanicolau (Pap) test. Mobile health has great potential in many health areas, particularly in healt...


Martínez Gutiérrez, Javiera.Soto, Mauricio.Capurro, Daniel.Puschel Illanes, Klaus.Momany, McKenzie C.Ciampi, Francis.Thompson, Beti.[Development of mobile technologies for the prevention of cervical cancer in Santiago, Chile study protocol : a randomized controlled trial]Development of mobile technologies for the prevention of cervical cancer in Santiago, Chile study protocol : a randomized controlled trial

Abstract We postulate that an orchestrated network composed of various vasodilatory systems participates in the systemic and local hemodynamic adaptations in pregnancy. The temporal patterns of increase in the circulating and urinary levels of five vasodilator factors/systems, prost...


Valdes, GloriaKaufmann, PeterCorthorn, JennyErices, RafaelaBrosnihan, K BJoyner-Grantham, JaNaeValdes, GloriaKaufmann, PeterCorthorn, JennyErices, RafaelaBrosnihan, K BJoyner-Grantham, JaNae[Vasodilator factors in the systemic and local adaptations to pregnancy]Vasodilator factors in the systemic and local adaptations to pregnancy

Abstract Background In utero interactions between incompatible maternal and fetal genotypes are a potential mechanism for the onset or progression of pregnancy related diseases such as pre-eclampsia (PE). However, the optimal analytical approach and ...


Parimi, NeetaTromp, GerardKuivaniemi, HelenaNien, Jyh K.Gomez, RicardoRomero, RobertoGoddard, Katrina A.[Analytical approaches to detect maternal/fetal genotype incompatibilities that increase risk of pre-eclampsia]Analytical approaches to detect maternal/fetal genotype incompatibilities that increase risk of pre-eclampsia

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