K channels mediate the selective passage of K+ across the plasma membrane by means of intimate interactions with ions at the pore selectivity filter located near the external face. Despite high conservation of the selectivity filter, the K+ transport properties of different K channels vary widely...
Díaz-Franulic, I.
,
Sepúlveda, R.V.
,
Navarro-Quezada, N.
,
González-Nilo, F.
,
Naranjo, D.
,
[Pore dimensions and the role of occupancy in unitary conductance of Shaker K channels]
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Pore dimensions and the role of occupancy in unitary conductance of Shaker K channels
Non-peptidic thrombin inhibitors (TIs; 177 compounds) with diverse groups at motifs P1 (such as oxyguanidine, amidinohydrazone, amidine, amidinopiperidine), P2 (such as cyano-fluorophenylacetamide, 2-(2-chloro-6-fluorophenyl)acetamide), and P3 (such as phenylethyl, arylsulfonate groups) were stud...
Mena-Ulecia, K.
,
Tiznado, W.
,
Caballero, J.
,
[Study of the Differential Activity of Thrombin Inhibitors Using Docking, QSAR, Molecular Dynamics, and MM-GBSA]
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Study of the Differential Activity of Thrombin Inhibitors Using Docking, QSAR, Molecular Dynamics, and MM-GBSA
The microdot method is a downscaling methodology of traditional tenfold serial dilution procedure used in microbiology. The microdot method uses 100 mu L for serial dilution and count colonies in a spot of 10 mu L. In this study we counted colonies directly in a chromogenic agar plate to determin...
El método de la microgota es una versión a menor escala del procedimiento tradicional de dilución en serie en base diez utilizados en microbiología. El método realiza diluciones en 100 µL y cuenta colonias crecidas en una gota de 10 µL. En este estudio se cuentan colonias directamente en placas c...
Strahsburger, Erwin
,
Retamales, Patricio
,
Estrada, Juan
,
Seeger, Michael
,
[Método de la microgota: usado con agar cromogénico es un procedimiento útil para el monitoreo sanitario en acuicultura]
,
[Microdot method: used with chromogenic agar is a useful procedure for sanitary monitoring in aquaculture]
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Microdot method: used with chromogenic agar is a useful procedure for sanitary monitoring in aquaculture
Context. Rapidly rotating, low-mass members of eclipsing binary systems have measured radii that are significantly larger than predicted by standard evolutionary models. It has been proposed that magnetic activity is responsible for this radius inflation.
Aims. By estimating the radii of low-ma...
Jackson, R. J.
,
Jeffries, R. D.
,
Randich, S.
,
Bragaglia, A.
,
Carraro, G.
,
Costado, M. T.
,
Flaccomio, E.
,
Lanzafame, A. C.
,
Lardo, C.
,
Monaco, L.
,
Morbidelli, L.
,
Smiljanic, R.
,
Zaggia, S.
,
[The Gaia-ESO Survey: Stellar radii in the young open clusters NGC 2264, NGC 2547, and NGC 2516]
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The Gaia-ESO Survey: Stellar radii in the young open clusters NGC 2264, NGC 2547, and NGC 2516
Introduction. 'Hass' is the main avocado cultivar commercialized worldwide. The extended flowering period, very low percentage of fruit set and inability to ripen on the tree renders the fruit heterogeneous and unpredictable during postharvest management. The "triggered" and "ready-to-eat" growin...
Hernandez, I
,
Fuentealba, C
,
Olaeta, JA
,
Lurie, S
,
Defilippi, BG
,
Campos-Vargas, R
,
Pedreschi, R
,
[Factors associated with postharvest ripening heterogeneity of "Hass" avocados (Persea americana Mill)]
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Factors associated with postharvest ripening heterogeneity of "Hass" avocados (Persea americana Mill)
Therapy for nonalcoholic steatohepatitis (NASH) is limited. Andrographolide (ANDRO), a botanical compound, has a potent anti-inflammatory activity due to its ability to inhibit NF-κB. ANDRO has been also shown to inhibit the NLRP3 inflammasome, a relevant pathway in NASH. Our aim was to evaluate ...
Cabrera, D.
,
Wree, A.
,
Povero, D.
,
Solís, N.
,
Hernandez, A.
,
Pizarro, M.
,
Moshage, H.
,
Torres, J.
,
Feldstein, A.E.
,
Cabello-Verrugio, C.
,
Brandan, E.
,
Barrera, F.
,
Arab, J.P.
,
Arrese, M.
,
[Andrographolide Ameliorates Inflammation and Fibrogenesis and Attenuates Inflammasome Activation in Experimental Non-Alcoholic Steatohepatitis]
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Andrographolide Ameliorates Inflammation and Fibrogenesis and Attenuates Inflammasome Activation in Experimental Non-Alcoholic Steatohepatitis
In the current educational setting, marked by a systematic increase in minority groups in classrooms and inequalities that are reproduced and modernized in educational contexts, the development of educational proposals modeled on the principles of inclusion, multiculturalism and social justice ga...
Vargas, F.J.
,
Sazatornil, J.L.L.
,
Cisternas, C.F.
,
[Learning, inclusion and social justice in multicultural educational environments]
,
[Aprendizajes, inclusión y justicia social en entornos educativos multiculturales]
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Aprendizajes, inclusión y justicia social en entornos educativos multiculturales
La Sentencia de la Corte de Apelaciones de Rancagua en el caso del Homicidio simple de Luis Almonacid Arellano, de fecha 14 de enero de 2013, aborda el tradicional tópico de la articulación entre el derecho internacional y el derecho interno, pero centrado, en este caso, en el campo específico de...
Aguilar Cavallo, Gonzalo
,
[Afinando las cuerdas de la especial articulación entre el derecho internacional de los Derechos Humanos y el derecho interno]
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Afinando las cuerdas de la especial articulación entre el derecho internacional de los Derechos Humanos y el derecho interno
Chronic peritoneal dialysis (PD) therapy is equally efficient as hemodialysis while providing greater patient comfort and mobility. Therefore, PD is the treatment of choice for several types of renal patients. During PD, a high-glucose hyperosmotic (HGH) solution is administered into the peritone...
Simon, F.
,
Tapia, P.
,
Armisen, R.
,
Echeverria, C.
,
Gatica, S.
,
Vallejos, A.
,
Pacheco, A.
,
Sanhueza, M.E.
,
Alvo, M.
,
Segovia, E.
,
Torres, R.
,
[Human peritoneal mesothelial cell death induced by high-glucose hypertonic solution involves Ca2+ and Na+ ions and oxidative stress with the participation of PKC/NOX2 and PI3K/Akt pathways]
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Human peritoneal mesothelial cell death induced by high-glucose hypertonic solution involves Ca2+ and Na+ ions and oxidative stress with the participation of PKC/NOX2 and PI3K/Akt pathways
Unfolded protein response (UPR) is a signaling mechanism activated by misfolded protein accumulation in the endoplasmic reticulum. It is a widespread process that has been described in organisms ranging from yeasts to mammals. In recent years, our understanding of UPR signaling pathway in plants ...
Moreno, Adrian
,
Orellana, Ariel
,
[The physiological role of the unfolded protein response in plants]
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The physiological role of the unfolded protein response in plants