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Fruit bodies of Cyttaria johowii which were often consumed by Amerindians were investigated for their secondary metabolites. Nine different sterols and sterones with the ergostane skeleton were found. The main components were dihydrobrassicasterol, ergost-4-en-3-one and (24S)-3β-hydroxyergost-5-e...


Insects of the genus Agathemera (Phasmatidae) live in the Chilean Andes over 1500 m above sea level. On disturbing, the insects release a spray that can cause temporary blindness in humans. Very little is known on the composition of chemicals used for defense by South American phasmids. Here we s...


Se diseñó un sistema de verificación experimental sobre la base de un prototipo, destinado a cuantificar el efecto cola de los inventarios. Los resultados obtenidos permiten concluir que un hospital puede reducir su inventario hasta en un 40%, mediante el uso de un sistema centralizado de informa...


The application of ligand-based drug design methods such as quantitative structure-activity relationship (QSAR) is a mandatory issue in the design of luteinizing hormone-releasing hormone (LHRH) receptor antagonists because the lack of information on the molecular structure for this target protei...


1,3-Dipolar cycloadditions of C-carboxymethyl-N-arylnitrile imines with cyclic α,β-unsaturated ketones of various sizes have been studied. After cycloaddition, oxidative aromatization gives the ring-fused pyrazoles. Computational studies and the use of topological analyses of the Fukui functions ...


The experimental oral carcinogenesis induced by the chemical 4-nitroquinoline 1-oxide (4NQO) is one of the most frequent in the study of squamous cell carcinoma of the oral cavity (CCEC). The clear advantage is that the model is very similar to the physiological process of malignancy. The model h...


Teletrabajo es una modalidad de trabajo que se proyecta como una de las opciones laborales de este siglo, han transcurrido muchos años en los que la investigación científica de las empresas se supeditó a desarrollar teorías y conceptos que iban en directa relación con los nuevos avances de la nat...


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