A raíz del incremento a nivel mundial de la prevalencia de sobrepeso y obesidad tanto en adultos como en niños, con consecuencias en la salud pública, la obesidad se ha convertido
en un blanco de estudio de diferentes grupos de investigación, lo que a su vez involucra el entendimiento del proceso...
González-Casanova, J.E.
,
Cruz, S.L.P.
,
Vivas, M.C.
,
Rojas-Gómez, D.M.
,
[Influence of endocrine disrupting chemicals on adipogénesis]
,
[Influencia de disruptores endocrinos medioambientales sobre la adipogénesis]
,
Influencia de disruptores endocrinos medioambientales sobre la adipogénesis
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease in which upper and lower motoneurons degenerate leading to muscle wasting, paralysis and eventually death from respiratory failure. Several studies indicate that skeletal muscle contributes to disease progression; however th...
Gonzalez, D.
,
Contreras, O.
,
Rebolledo, D.L.
,
Espinoza, J.P.
,
Van Zundert, B.
,
Brandan, E.
,
[ALS skeletal muscle shows enhanced TGF-β signaling, fibrosis and induction of fibro/adipogenic progenitor markers]
,
ALS skeletal muscle shows enhanced TGF-β signaling, fibrosis and induction of fibro/adipogenic progenitor markers
The final product of adipogenesis is a functional adipocyte. This mature cell acquires the necessary machinery for lipid metabolism, loses its proliferation potential, increases its insulin sensitivity, and secretes adipokines. Multipotent mesechymal stromal cells have been recognized as a source...