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A whole farm simulation model, Technology Impact Evaluation System (TIES), was used to assess ex-ante financial and economic impacts of immunization of dairy cattle against East Coast fever (ECF) by the infection and treatment method (ITM) on smallholder farms from two sites in Kenya. Four altern...


Nyangito, H.O.Richardson, J.W.Mundy, D.S.Mukhebi, A.W.Zimmel, P.Namken, J.[Economic impacts of East Coast fever immunization on smallholder farms, Kenya: A simulation analysis]Economic impacts of East Coast fever immunization on smallholder farms, Kenya: A simulation analysis
Amzati, Gaston S.Pelle, RogerMuhigwa, J.B.Kanduma, E.G.Djikeng, AppolinaireMadder, M.Kirschvink, N.Marcotty, T.[Mitochondrial phylogeography and population structure of the cattle tick Rhipicephalus appendiculatus in the African Great Lakes region]Mitochondrial phylogeography and population structure of the cattle tick Rhipicephalus appendiculatus in the African Great Lakes region

East Coast fever (ECF) caused by Theileria parva kills cattle in East, Central and Southern Africa leading to significant economic losses. Vaccination is used as a control strategy against ECF and is presently dependent on deliberate infection with live sporozoites and simultaneous treatment with...


Nyagwange, JamesNene, VishvanathMwalimu, Stephen M.Henson, Sonal P.Steinaa, LucillaNzau, Benjamin M.Tijhaar, EdwinPelle, Roger[Antibodies to in silico selected GPI-anchored Theileria parva proteins neutralize sporozoite infection in vitro]Antibodies to in silico selected GPI-anchored Theileria parva proteins neutralize sporozoite infection in vitro
Fawcett, D.W.Doxsey, S.Buscher, G.[Salivary gland of the tick vector (R. appendiculatus) of East Coast fever. II. Cellular basis for fluid secretion in the type III acinus]Salivary gland of the tick vector (R. appendiculatus) of East Coast fever. II. Cellular basis for fluid secretion in the type III acinus
Fawcett, D.W.Doxsey, S.Buscher, G.[Salivary gland of the tick vector (R. appendiculatus) of East Coast fever. I. Ultrastructure of the type III acinus]Salivary gland of the tick vector (R. appendiculatus) of East Coast fever. I. Ultrastructure of the type III acinus
Fawcett, D.W.Buscher, G.Doxsey, S.[Salivary gland of the tick vector of East Coast fever. III. The ultrastructure of sporogony in Theileria parva]Salivary gland of the tick vector of East Coast fever. III. The ultrastructure of sporogony in Theileria parva

The purpose of the study was to characterize the differences in epidemiology (risks of infection. morbidity. mortality) and potential control of East Coast fever (ECF) between the selected strata. Evidence of Theileria parva infection was assessed by increased antibody levels as measured in an in...


Gitau, G.K.McDermott, John J.Katende, J.M.Perry, Brian D.[The epidemiology of Theileria parva infections on smallholder dairy farms in Kenya]The epidemiology of Theileria parva infections on smallholder dairy farms in Kenya

We investigated the perceived impact of malignant catarrhal fever (MCF) to pastoralists in Isinya Division, a wildlife dispersal area of Nairobi National Park, and used a range of participatory epidemiology methodologies. We compared the relative importance, incidence and impact of MCF compared t...


Bedelian, ClaireNkedianye, D.Herrero, Mario T.[Maasai perception of the impact and incidence of malignant catarrhal fever (MCF) in southern Kenya]Maasai perception of the impact and incidence of malignant catarrhal fever (MCF) in southern Kenya

Objectives: The objective of this study was to assess whether cytotoxic T cells (CTL) generated by the live vaccine, known as “ITM Muguga cocktail”, which is used for the cattle disease East Cost fever (ECF) in Sub-Saharan Africa, showed a broad reactivity against many different strains of the ca...


Steinaa, LucillaSvitek, NicholasAwino, EliasSaya, RosemaryToye, Philip G.[Cytotoxic T lymphocytes from cattle sharing the same MHC class I haplotype and immunized with live Theileria parva sporozoites differ in antigenic specificity]Cytotoxic T lymphocytes from cattle sharing the same MHC class I haplotype and immunized with live Theileria parva sporozoites differ in antigenic specificity

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