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A modified NC membrane-based dot-ELISA was used to detect and differentiate between Trypanosoma brucei, T. congolense and T. simiae procyclics in the midguts of experimentally infected tsetse flies. The modification of the assay consisted of (a) the lysis of T. congolense or T. simiae in NC membr...


Bosompem, K.M.Moloo, S.K.Assoku, R.K.G.Nantulya, V.M.[Detection and differentiation between trypanosome species in experimentally infected tsetse flies (Glossina spp.) using dot-ELISA]Detection and differentiation between trypanosome species in experimentally infected tsetse flies (Glossina spp.) using dot-ELISA

Tsetse fly populations have been monitored since January 1986 in two areas of the Ghibe valley in southwest Ethiopia, in order to assess trypanosomiasis risk to cattle. The two study areas are Abelti/Ghibe and Gullele/Tolley. Two species of tsetse fly were detected in the valley from 1986 to 1992...


Leak, S.G.A.Mulatu, W.[Advance of Glossina morsitans submorsitans and G. pallidipes along the Ghibe-river system in southwest Ethiopia]Advance of Glossina morsitans submorsitans and G. pallidipes along the Ghibe-river system in southwest Ethiopia
Sutherland, I.A.Moloo, S.K.Holmes, P.H.Peregrine, A.S.[Therapeutic and prophylactic activity of isometamidium chloride against a tsetse-transmitted drug-resistant clone of Trypanosoma congolense in Boran cattle]Therapeutic and prophylactic activity of isometamidium chloride against a tsetse-transmitted drug-resistant clone of Trypanosoma congolense in Boran cattle
Claxton, J.R.Leperre, P.Rawlings, P.Snow, W.F.Dwinger, R.H.[Trypanosomiasis in cattle in Gambia: Incidence, prevalence and tsetse challenge]Trypanosomiasis in cattle in Gambia: Incidence, prevalence and tsetse challenge
Rovis, L.Musoke, A.J.Moloo, S.K.[Failure of trypanosomal membrane antigens to induce protection against tsetse-transmitted Trypanosoma vivax or Trypanosoma brucei in goats and rabbits]Failure of trypanosomal membrane antigens to induce protection against tsetse-transmitted Trypanosoma vivax or Trypanosoma brucei in goats and rabbits
Moloo, S.K.Zweygarth, E.Sabwa, C.L.[Comparative study on the susceptibility of different laboratory strains of Glossina species to Trypanosoma simiae]Comparative study on the susceptibility of different laboratory strains of Glossina species to Trypanosoma simiae

The first visible response in livestock to the bite of a trypanosome-infected tsetse fly is the formation of a localized skin reaction, also known as a chancre. This is an inflammatory response in the skin associated with swelling and an influx of cells. It is thought to be associated with an a...


Naessens, JanMwangi, D.M.Buza, J.Moloo, S.K.[Local skin reaction (chancre) induced following inoculation of metacyclic trypanosomes in cattle by tsetse flies is dependent on CD4 T lymphocytes]Local skin reaction (chancre) induced following inoculation of metacyclic trypanosomes in cattle by tsetse flies is dependent on CD4 T lymphocytes

This paper discusses past and present approaches to managing tsetse-transmitted animal trypanosomosis in Africa and describes the three main weaknesses of these approaches, i.e., inappropriate objectives, inadequate links between research and policy-making and a lack of recognition that trypano...


Omamo, S.W.D'Ieteren, G.D.M.[Managing animal trypanosomosis in Africa: Issues and options]Managing animal trypanosomosis in Africa: Issues and options
Dwinger, R.H.Luckins, G.Murray, M.Rae, P.Moloo, S.K.[Interference between different serodemes of Trypanosoma congolense in the establishment of superinfections in goats following transmission by tsetse]Interference between different serodemes of Trypanosoma congolense in the establishment of superinfections in goats following transmission by tsetse
Nantulya, V.M.[An antigen detection enzyme immunoassay for the diagnosis of Rhodesiense sleeping sickness]An antigen detection enzyme immunoassay for the diagnosis of Rhodesiense sleeping sickness

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