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Reprimo (RPRM) is a potential p53-dependent tumor suppressor gene, which plays an important role in cell cycle arrest at G(2)/M checkpoint. The aim of this study was to characterize RPRM protein expression in breast cancer tissues and its relation with clinic-pathologic features and proliferation...
Despite continuous advances in the knowledge of breast cancer pathophysiology, this type of neoplasia remains a leading cause of cancer-related death in women worldwide. Carcinogenesis takes a progressive course from somatic mutations, alteration of the DNA repair mechanisms, inhibition of growth...
GPER-1 is a novel membrane sited G protein-coupled estrogen receptor. Clinical studies have shown that patients suffering an estrogen receptor alpha (ER alpha)/GPER-1 positive, breast cancer have a lower survival rate than those who have developed ER alpha-positive/GPER-1 negative tumors. Moreove...
Self-perception of upper limbs swelling can be an effective tool in diagnostic and early intervention of lymphedema. The aim of the present paper was to verify the association between self-perception of swelling of upper extremities and objective criteria commonly used for lymphedema diagnostic i...
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