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Murine models have suggested that CD8 T cells might play a major parasite-promoting role in African trypanosomiasis. To assess the role of these cells in a natural host environment, we have depleted CD8 cells from Boran cattle in vivo and subsequently infected these animals with Trypanosoma congo...


Sileghem, M.R.Naessens, Jan[Are CD8 T cells involved in control of African trypanosomiasis in a natural host environment?]Are CD8 T cells involved in control of African trypanosomiasis in a natural host environment?

A bioassay was used to measure erythropoietin (EPO) concentrations in calves with haemorrhagic anaemia due to blood loss and in calves with anaemia due to Trypanosoma congolense infection. The bioactivity of EPO was measured in the assay by its stimulatory effect on 125I-deoxyuridine incorporatio...


Buza, J.J.Logan-Henfrey, L.L.Andrianarivo, A.G.Williams, D.J.L.[Rise in erythropoietin concentrations in experimental Trypanosoma congolense infection of calves]Rise in erythropoietin concentrations in experimental Trypanosoma congolense infection of calves

Nuclear extrachromosomal DNA elements have been identified in several kinetoplastids such as Leishmania and Trypanosoma cruzi, but never in Trypanosoma brucei. They can occur naturally or arise spontaneously as the result of sublethal drug exposure of parasites. In most cases, they are represente...


Alsford, N.S.Navarro, M.Jamnadass, Ramni H.Dunbar, H.Ackroyd, M.Murphy, N.B.Gull, K.Ersfeld, K.[The identification of circular extrachromosomal DNA in the nuclear genome of Trypanosoma brucei]The identification of circular extrachromosomal DNA in the nuclear genome of Trypanosoma brucei

International Laboratory for Research on Animal Diseases[ILRAD Reports. Volume 1. Number 2. October 1983]ILRAD Reports. Volume 1. Number 2. October 1983

International Laboratory for Research on Animal Diseases[ILRAD Reports. Volume 10. Number 4. October 1992]ILRAD Reports. Volume 10. Number 4. October 1992

International Laboratory for Research on Animal Diseases[ILRAD Reports. Volume 2. Number 3. July 1984]ILRAD Reports. Volume 2. Number 3. July 1984

International Laboratory for Research on Animal Diseases[ILRAD Reports. Volume 5. Number 2. April 1987]ILRAD Reports. Volume 5. Number 2. April 1987

International Laboratory for Research on Animal Diseases[ILRAD Reports. Volume 8. Number 2. April 1990]ILRAD Reports. Volume 8. Number 2. April 1990

International Laboratory for Research on Animal Diseases[ILRAD Reports. Volume 12. Numbers 1 & 2. January-June 1994]ILRAD Reports. Volume 12. Numbers 1 & 2. January-June 1994

International Laboratory for Research on Animal Diseases[ILRAD Reports. Volume 4. Number 1. January 1986]ILRAD Reports. Volume 4. Number 1. January 1986

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