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The TNF-alfa gene on mouse chromosome MMU17 is among the candidates for the trypanosomosis resistance QTG Tirl. Tit t has the largest effect of those loci so far detected which influence degree of resistance to murine trypanosomosis caused by Trypanosome congolense infection. We therefore studied...


Iraqi, F.A.Sekikawa, K.Rowlands, G.J.Teale, A.J.[Susceptibility of tumour necrosis factor-alpha genetically deficient mice to Trypanosoma congolense infection]Susceptibility of tumour necrosis factor-alpha genetically deficient mice to Trypanosoma congolense infection

A survey to investigate resistance to drugs used in the treatment of bovine trypanosomosis was conducted in the eastern province of Zambia between 1996 and 1998. A cross-sectional study was conducted in three districts (Petauke, Katete, Lundazi) at 34 village sampling sites selected at random fr...


Sinyangwe, L.Delespaux, V.Brandt, J.Geerts, S.Mubanga, J.Machila, N.Holmes, P.H.Eisler, M.C.[Trypanocidal drug resistance in eastern province of Zambia]Trypanocidal drug resistance in eastern province of Zambia

Tsetse fly-transmitted trypanosomes (Trypanosoma spp.) cause 'sleeping sickness' in man and have a serious impact on livestock-based agriculture in large areas of Africa. Multigene control of variation in susceptibility to trypanosomiasis is known to occur in mice, where the C57BI/6 (B6) strain i...


Kemp, Stephen J.Iraqi, F.A.Darvasi, A.Soller, M.Teale, A.J.[Localization of genes controlling resistance to trypanosomiasis in mice]Localization of genes controlling resistance to trypanosomiasis in mice

Trypanosomiasis is one of the major constraints on animal production in areas of Africa that have the greatest potential for significant increases in domestic livestock populations and livestock productivity. While various methods are being used by farmers to control the disease, major public eff...


D'Ieteren, G.D.M.Kimani, K.[Indigenous genetic resources: A sustainable and environmentally friendly option for livestock production in areas at risk from trypanosomosis]Indigenous genetic resources: A sustainable and environmentally friendly option for livestock production in areas at risk from trypanosomosis

Discusses trypanotolerance in cattle and prospects for the control of trypanosomiasis by selective breeding in Africa. Looks into methods available for control including tsetse control, drugs & vaccination and discusses constraints that limit the control. Also discusses prospects for future contr...


Murray, M.Trail, J.C.M.D'Ieteren, G.D.M.[Trypanotolerance in cattle and prospects for the control of trypanosomiasis by selective breeding]Trypanotolerance in cattle and prospects for the control of trypanosomiasis by selective breeding

The shift towards community participation in the eradication of trypanosomosis calls for investigation the underlying incentive structure for individuals in the community to cooperate in the provision of various control methods. Survey data were used to assess patterns of the community's demand f...


Somda, JacquesKamuanga, M.Tollens, E.F.[Prospective analysis for community participation in trypanosomosis control in The Gambia]Prospective analysis for community participation in trypanosomosis control in The Gambia

During this century livestock production has increased massively through the improved ability to diagnose, treat, control and prevent certain diseases. Despite these advances, disease remains a major constraint to livestock production and welfare throughout the world. In many instances, this is a...


Gu, Y.Gettinby, G.McKendrick, I.Murray, M.Peregrine, A.S.[Development of a decision support system for trypanocidal drug control of bovine trypanosomosis in Africa]Development of a decision support system for trypanocidal drug control of bovine trypanosomosis in Africa
Fèvre, Eric M.Wissmann, B.V.Welburn, S.C.Lutumba, P.[The burden of human African trypanosomiasis]The burden of human African trypanosomiasis

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