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In this thesis firstly we study the existence of T−periodic solutions to the second order differential equation $$u′′ =\frac{ h(t)}{u^\lambda}.$$ Here $h \in L(\mathbb{R}/T\mathbb{Z})$ is a piecewise constant sign-changing function and the non- linear term presents a weak singularity at 0 (i.e....

En esta tesis comenzamos por estudiar la existencia de soluciones T−periódicas para la ecuación diferencial de segundo orden $$u′′ =\frac{ h(t)}{u^\lambda}.$$ Aqui $h \in L(\mathbb{R}/T\mathbb{Z}) es un función constante a tramos, que cambia de signo, y el término no lineal presenta una singula...


We introduce a condition on Garside groups that we call Dehornoy structure. An iteration of such a structure leads to a left order on the group. We show conditions for a Garside group to admit a Dehornoy structure, and we apply these criteria to prove that the Artin groups of type A and I2(m), m ...


Aldosterone (ALDO), through the activation of the mineralocorticoid receptor (MR) on epithelial cells from the distal nephron (DN), stimulates renal sodium reabsorption increasing circulatory blood volume and hence, blood pressure. Additionally, the increase of sodium reabsorption ...

Aldosterona (ALDO), a través de la activación del receptor de mineralocorticoides (MR) expresado en células epiteliales del nefrón distal (ND), estimula la reabsorción de sodio renal aumentando el volumen sanguíneo circulante y con ello la presión arterial. Adicionalmente...


The reduction of fossil fuels, in addition to the serious pollution caused by their use, is a global problem. This has led humanity to think about new alternatives for the production of clean, economic and renewable energies. Among the energies that present these characteristics is solar energy, ...

La disminución de combustibles fósiles, además de la grave contaminación que produce su utilización es un problema a nivel mundial, lo anterior ha llevado a la humanidad a pensar en nuevas alternativas para la producción de energías limpias, económicas y renovables. Dentro de las energías que pre...


In the present doctoral thesis, the main focus was the study of the phosphoryl transfer mechanism in the protein cyclin-dependent kinase 2 (CDK2). For this, different computational methods such as molecular dynamics (MD) simulations, quantum chemical calculations, and in particular hybrid QM/MM (...


Trust-repayment behavior is crucial to establish and maintain cooperative links between different (even genetically unrelated) individuals. However, neither the exact nature of this behavior considered mainly as reciprocity, an intentions-based behavior), nor its underlying neural basis, re cle...


La homeostasis de la glucosa es un mecanismo fisiológicamente balanceado que depende fundamentalmente de la secreción de insulina por parte de las células β pancreáticas y de la translocación de GLUT4 a la membrana plasmática. Ambos eventos de fusión de membranas son mediados por la familia de pr...

Glucose homeostasis is a physiologically balanced mechanism that depends mainly on the secretion of insulin by pancreatic β cells and the translocation of GLUT4 to the plasma membrane. Both membrane fusion events are mediated by the SNAREs family of proteins and the absence of proteins from th...


We study the propagation and distribution of quantum correlations through two chains of atoms inside cavities joined by optical fibres. This system is interesting because it can be used as a channel for quantum communication or as a network for quantum co


Food waste is considered a social, environmental and economic problem. Concerns are based, amongst other things, on the environmental damage produced by the food supply chain (FSC) and the substantial amount of food that is wasted. This work reviews the relationship between food waste and the en...


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