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Contagious caprine pleuropneumonia (CCPP) caused by Mycoplasma capricolum subsp. capripneumoniae is a severe epidemic affecting mainly domestic Caprinae species but also affects wild Caprinae species. M. capricolum subsp. capripneumoniae belongs to the “Mycoplasma mycoides cluster.” The disease f...


Falquet, LaurentLiljander, Anne M.Schieck, Elise G.Gluecks, Ilona V.Frey, J.Jores, Joerg[Complete genome sequences of virulent Mycoplasma capricolum subsp. capripneumoniae strains F38 and ILRI181]Complete genome sequences of virulent Mycoplasma capricolum subsp. capripneumoniae strains F38 and ILRI181

Mycoplasma mycoides subsp. capri (Mmc) and subsp. mycoides (Mmm) are important ruminant pathogens worldwide causing diseases such as pleuropneumonia, mastitis and septicaemia. They express galactofuranose residues on their surface, but their role in pathogenesis has not yet been determined. The M...


Schieck, Elise G.Lartigue, C.Frey, J.Vozza, N.Hegermann, J.Miller, R.A.Valguarnera, E.Muriuki, C.Meens, J.Nene, VishvanathNaessens, JanWeber, J.Lowary, T.L.Vashee, S.Feldman, M.F.Jores, Joerg[Galactofuranose in Mycoplasma mycoides is important for membrane integrity and conceals adhesins but does not contribute to serum resistance]Galactofuranose in Mycoplasma mycoides is important for membrane integrity and conceals adhesins but does not contribute to serum resistance

Peste des petits ruminants virus (PPRV) causes an economically important disease of sheep and goats, primarily in developing countries. It is becoming the object of intensive international control efforts. Current vaccines do not allow vaccinated and infected animals to be distinguished (no DIVA ...


Holzer, B.Taylor, G.Rajko-Nenow, P.Hodgson, S.Okoth, Edward A.Herbert, R.Toye, Philip G.Baron, M.D.[Determination of the minimum fully protective dose of adenovirus-based DIVA vaccine against peste des petits ruminants virus challenge in East African goats]Determination of the minimum fully protective dose of adenovirus-based DIVA vaccine against peste des petits ruminants virus challenge in East African goats

Contagious caprine pleuropneumonia (CCPP) is a highly contagious disease caused by Mycoplasma capricolum subsp. capripneumoniae that affects goats in Africa and Asia. Current available methods for the diagnosis of Mycoplasma infection, including cultivation, serological assays, and PCR, are time-...


Liljander, Anne M.Mingyan YuO'Brien, E.Heller, M.Nepper, J.F.Weibel, D.B.Gluecks, Ilona V.Younan, M.Frey, J.Falquet, LaurentJores, Joerg[Field-applicable recombinase polymerase amplification assay for rapid detection of Mycoplasma capricolum subsp. Capripneumonia]Field-applicable recombinase polymerase amplification assay for rapid detection of Mycoplasma capricolum subsp. Capripneumonia

Derda, R.Gitaka, J.Klapperich, C.M.Mace, C.R.Kumar, A.A.Lieberman, M.Linnes, J.C.Jores, JoergNasimolo, J.Ndung'u, J.M.Taracha, E.A.Weaver, A.Weibel, D.B.Kariuki, T.M.Yager, P.[Enabling the development and deployment of next generation point-of-care diagnostics]Enabling the development and deployment of next generation point-of-care diagnostics

Background In mid-2015, the United States’ Pandemic Prediction and Forecasting Science and Technical Working Group of the National Science and Technology Council, Food and Agriculture Organization Emergency Prevention Systems, and Kenya Meteorological Department issued an alert predicting a high ...


Oyas, H.Holmstrom, L.Kemunto, N.P.Muturi, M.Mwatondo, A.Osoro, E.Bitek, A.Bett, Bernard K.Githinji, J.W.K.Thumbi, S.M.Widdowson, M.-A.Munyua, P.M.Njenga, M.K.[Enhanced surveillance for Rift Valley fever in livestock during El Niño rains and threat of RVF outbreak, Kenya, 2015-2016]Enhanced surveillance for Rift Valley fever in livestock during El Niño rains and threat of RVF outbreak, Kenya, 2015-2016

Stahl, K.Ogweng, P.Okoth, Edward A.Aliro, T.Muhangi, D.LeBlanc, N.Atimnedi, P.Berg, M.Bishop, Richard P.Rasmussen, H.B.Masembe, C.[Understanding the dynamics and spread of African Swine fever at the wildlife livestock interface: Insights into the potential role of the bushpig Potamochoerus larvatus]Understanding the dynamics and spread of African Swine fever at the wildlife livestock interface: Insights into the potential role of the bushpig Potamochoerus larvatus

Avian malaria parasites are prevalent around the world and infect a wide diversity of bird species. Here, we report the sequencing and analysis of high-quality draft genome sequences for two avian malaria species, Plasmodium relictum and Plasmodium gallinaceum. We identify 50 genes that are speci...


Böhme, U.Otto, T.D.Cotton, J.A.Steinbiss, S.Sanders, M.Oyola, Samuel O.Nicot, A.Gandon, S.Patra, K.P.Herd, C.Bushell, E.Modrzynska, K.K.Billker, O.Vinetz, J.M.Rivero, A.Newbold, C.J.Berriman, M.[Complete avian malaria parasite genomes reveal features associated with lineage-specific evolution in birds and mammals]Complete avian malaria parasite genomes reveal features associated with lineage-specific evolution in birds and mammals

Tick-borne diseases are a major impediment to improved productivity of livestock in sub-Saharan Africa. Improved control of these diseases would be assisted by detailed epidemiological data. Here we used longitudinal, serological data to determine the patterns of exposure to Theileria parva, Thei...


Kiara, Henry K.Jennings, A.Bronsvoort, B.M. de C.Hande, I.G.Mwangi, S.T.Mbole-Kariuki, Mary N.Wyk, I.C. vanPoole, Elizabeth J.Hanotte, Olivier H.Coetzer, J.A.W.Woolhouse, Mark E.J.Toye, Philip G.[A longitudinal assessment of the serological response to Theileria parva and other tick-borne parasites from birth to one year in a cohort of indigenous calves in western Kenya]A longitudinal assessment of the serological response to Theileria parva and other tick-borne parasites from birth to one year in a cohort of indigenous calves in western Kenya

Parasite burden varies widely between individuals within a population, and can covary with multiple aspects of individual phenotype. Here we investigate the sources of variation in faecal strongyle eggs counts, and its association with body weight and a suite of haematological measures, in a coho...


Callaby, R.Hanotte, Olivier H.Wyk, I.C. vanKiara, Henry K.Toye, Philip G.Mbole-Kariuki, Mary N.Jennings, A.Thumbi, S.M.Coetzer, J.A.W.Bronsvoort, B.M. de C.Knott, S.A.Woolhouse, Mark E.J.Kruuk, L.E.B.[Variation and covariation in strongyle infection in East African shorthorn zebu calves]Variation and covariation in strongyle infection in East African shorthorn zebu calves

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