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Trypanosomosis is the most economically important disease constraint to livestock productivity in sub-Saharan Africa and has significant negative impact in other parts of the world. Livestock are an integral component of farming systems and thus contribute significantly to food and economic secur...


Taylor, K.A.Mertens, B.[Immune responses of cattle to African trypanosomes: Protective or pathogenic?]Immune responses of cattle to African trypanosomes: Protective or pathogenic?

A marker-assisted introgression (MAI) experiment was conducted to use genetic markers to transfer each of the three trypanotolerance QTL from a donor mouse strain, C57BL/6, into a recipient mouse strain, A/J. We used a backcross strategy that consisted of selecting two lines, each carrying two of...


Koudande, O.D.Arendonk, Johan A.M. vanIraqi, F.A.[Marker-assisted introgression of trypanotolerance QTL in mice]Marker-assisted introgression of trypanotolerance QTL in mice

It has been reported that some breeds of cattle such as the N'Dama mount a more effective antibody response to the variable surface glycoprotein coat of trypanosomes and that this may contribute to their ability to control the infection. Thus we have investigated antibody responses to surface exp...


Williams, D.J.L.Taylor, K.Newson, J.Gichuki, B.Naessens, Jan[The role of anti-variable surface glycoprotein antibody responses in bovine trypanotolerance]The role of anti-variable surface glycoprotein antibody responses in bovine trypanotolerance
Katende, J.Nantulya, V.M.Musoke, A.J.[Comparison between bloodstream and procyclic form trypanosomes for serodiagnosis of African human trypanosomiasis]Comparison between bloodstream and procyclic form trypanosomes for serodiagnosis of African human trypanosomiasis
Murray, M.Murray, P.K.McIntyre, W.I.M.[An improved parasitological technique for the diagnosis of African trypanosomiasis]An improved parasitological technique for the diagnosis of African trypanosomiasis
Stebeck, C.E.Pearson, T.W.[Major surface glycoproteins of procyclic stage African trypanosomes]Major surface glycoproteins of procyclic stage African trypanosomes

In part I of this review of the prospects of vaccination against African trypanosomiasis, contained in the previous issue of World Animal Review, the constraints in developing a vaccine were discussed and current knowledge on the molecular biology of the trypanosome and on antigenic variation wit...


Murray, M.Barry, J.D.Morrison, W. IvanWilliams, R.O.Hirumi, H.Rovis, L.A.[A review of the prospects for vaccination in African trypanosomiasis. Part II]A review of the prospects for vaccination in African trypanosomiasis. Part II

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