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Bacteriophage clones containing Theileria parva genomic DNA derived from two different telomeres were isolated and the nucleotide sequences of the telomeric repeats and adjacent telomere-associated (TAS) DNA were determined. The T. parva telomeric repeat sequences, a tandem array of TTTTAGGG or T...


Sohanpal, B.K.Morzaria, S.P.Gobright, E.I.Bishop, Richard P.[Characterisation of the telomeres at opposite ends of a 3 Mb Theileria parva chromosome]Characterisation of the telomeres at opposite ends of a 3 Mb Theileria parva chromosome
Masake, R.A.Nyambati, V.M.Nantulya, V.M.Majiwa, P.A.O.Moloo, S.K.Musoke, A.J.[The chromosome profiles of Trypanosoma congolense isolates from Kilifi, Kenya and their relationship to serodeme identity]The chromosome profiles of Trypanosoma congolense isolates from Kilifi, Kenya and their relationship to serodeme identity

The paper first describes interleukin-12 P35 encoding gene and discusses its role. It then looks into PCR conditions and sequencing; genotyping; sequencing; polymorphism frequency; mendelian inheritance; chromosomal location in sheep and cattle of different species.


Schmidt, P.Kuhn, C.Kang'a, S.Hanotte, Olivier H.Vanselow, J.Anton, I.Langner, ChSchwerin, M.[Interleukin - 12 p35 encoding gene of cattle and sheep harbours a polymorphic T stretch in intron 4]Interleukin - 12 p35 encoding gene of cattle and sheep harbours a polymorphic T stretch in intron 4

A marker-assisted introgression (MAI) experiment was conducted to transfer trypanotolerance quantitative trait loci (QTL) from a donor mouse strain, C57BL/6, into a recipient mouse strain, A/J. The objective was to assess the effect of three previously identified chromosomal regions on mouse chro...


Koudande, O.D.Thomson, P.C.Bovenhuis, H.Iraqi, F.A.Gibson, John P.Arendonk, Johan A.M. van[Biphasic survival analysis of trypanotolerance QTL in mice]Biphasic survival analysis of trypanotolerance QTL in mice

A number of linkage studies in human populations have identified a locus ( pfbi) on Chromosome 5q31-q33 controlling Plasmodiun falciparum blood infection levels. This region contains numerous candidate genes encoding immunological molecules such as cytokines, growth factors and growth-factor rec...


Hernández Valladares, M.Rihet, P.Ole-MoiYoi, O.K.Iraqi, F.A.[Mapping of a new quantitative trait locus for resistance to malaria in mice by a comparative mapping approach with human chromosome 5q31-q33]Mapping of a new quantitative trait locus for resistance to malaria in mice by a comparative mapping approach with human chromosome 5q31-q33

Most banana cultivars are triploid seedless parthenocarpic clones derived from hybridization between Musa acuminata subspecies and sometimes M. balbisiana. M. acuminata subspecies were suggested to differ by a few large chromosomal rearrangements based on chromosome pairing configurations in inte...


Martin, G.Carreel, F.Coriton, O.Hervouet, C.Cardi, C.Derouault, P.Roques, D.Salmon, F.Rouard, M.Sardos, J.Labadie, KarineBaurens, F.C.D’Hont, A.[Evolution of the banana genome (Musa acuminata) is impacted by large chromosomal translocations]Evolution of the banana genome (Musa acuminata) is impacted by large chromosomal translocations

Admixture and polyploidization are major recognized eukaryotic genome evolutionary processes. Their impacts on genome dynamics vary among systems and are still partially deciphered. Many banana cultivars are triploid (sometimes diploid) interspecific hybrids between Musa acuminata (A genome) and ...


Baurens, F.C.Martin, G.Hervouet, C.Salmon, F.Yohoume D.Ricci, S.Rouard, M.Habas, R.Yahiaoui, N.D’Hont, A.[Recombinations and large structural variations shape the mosaic genomes of interspecific edible bananas]Recombinations and large structural variations shape the mosaic genomes of interspecific edible bananas

A small number of west African Bos taurus cattle breeds, including the N'Dama, constitute a valuable genetic resource by virtue of their ability to remain productive under trypanosomiasis challenge. However, introgression of Bos indicus genes into the trypanotolerant breeds, particularly by intro...


Teale, A.J.Wambugu, J.Gwakisa, P.S.Stranzinger, G.Bradley, D.Kemp, Stephen J.[A polymorphism in randomly amplified DNA which differentiates the Y chromosomes of Bos indicus and Bos taurus]A polymorphism in randomly amplified DNA which differentiates the Y chromosomes of Bos indicus and Bos taurus

When compared with other Apicomplexan organisms. Theileria parva has an execptionally small, 10-12 Mbp. genome. There are only 4 chromosomes, each in the Mbp range, and a complete physical map, based on SfiI linking data, is available for each one. A number of genes and cDNAs have been mapped to ...


Nene, VishvanathMorzaria, S.P.Bishop, Richard P.[Organisation and informational content of the Theileria parva genome]Organisation and informational content of the Theileria parva genome

This paper reports the results of a genome-wide search for quantitative trait loci (QTL) influencing immunological responses to infection with the gastro-intestinal nematode parasite Heligmosomoides polygyrus in an F2 population created by crossing the resistant SWR and the susceptible CBA inbr...


Menge, D.M.Behnke, J.M.Lowe, A.Gibson, John P.Iraqi, F.A.Baker, R.L.Wakelin, D.[Mapping of chromosomal regions influencing immunological responses to gastrointestinal nematode infections in mice]Mapping of chromosomal regions influencing immunological responses to gastrointestinal nematode infections in mice

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