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The infection-and-treatment method (ITM) for immunization of cattle against East Coast fever has historically been used only on a limited scale because of logistical and policy constraints. Recent large-scale deployment among pastoralists in Tanzania has stimulated demand. Concurrently, a suite o...


Giulio, Giuseppe diLynen, GodelieveMorzaria, S.P.Oura, C.Bishop, Richard P.[Live immunization against East Coast fever - current status]Live immunization against East Coast fever - current status

The published genomic sequences of the two major host-transforming Theileria species of cattle represent a rich resource of information that has allowed novel bioinformatic and experimental studies into these important apicomplexan parasites. Since their publication in 2005, the genomes of T. ann...


Weir, W.Sunter, J.Chaussepied, M.Skilton, Robert A.Tait, A.Villiers, Etienne P. deBishop, Richard P.Shiels, B.Langsley, G.[Highly syntenic and yet divergent: a tale of two Theilerias]Highly syntenic and yet divergent: a tale of two Theilerias

Theileria parva causes East Coast fever, an economically important disease of cattle in sub-Saharan Africa. We describe a nested polymerase chain reaction (nPCR) assay for the detection of T. parva DNA in cattle blood spotted onto filter paper using primers derived from the T. parva-specific 104-...


Odongo, David O.Sunter, J.D.Kiara, Henry K.Skilton, Robert A.Bishop, Richard P.[A nested PCR assay exhibits enhanced sensitivity for detection of Theileria parva infections in bovine blood samples from carrier animals]A nested PCR assay exhibits enhanced sensitivity for detection of Theileria parva infections in bovine blood samples from carrier animals

We have developed two loop-mediated isothermal amplification (LAMP) assays for the detection of Theileria parva, the causative agent of East Coast fever (ECF), an economically important cattle disease in eastern, central and southern Africa. These assays target the polymorphic immunodominant mole...


Thekisoe, O.M.M.Rambritch, N.E.Nakao, R.Bazie, R.S.Mbati, P.Namangala, B.Malele, I.Skilton, Robert A.Jongejan, F.Sugimoto, C.Kawazu, S.I.Inoue, N.[Loop-mediated isothermal amplification (LAMP) assays for detection of Theileria parva infections targeting the PIM and p150 genes]Loop-mediated isothermal amplification (LAMP) assays for detection of Theileria parva infections targeting the PIM and p150 genes
Nyangito, H.O.Richardson, J.W.Mukhebi, A.W.Mundy, D.S.Zimmel, P.Namken, P.Perry, Brian D.[Whole farm economic analysis of East Coast fever immunization strategies in Kilifi District, Kenya]Whole farm economic analysis of East Coast fever immunization strategies in Kilifi District, Kenya
Mukhebi, A.W.Morzaria, S.P.Perry, Brian D.Dolan, T.T.Norval, R.A.I.[Cost analysis of immunization of East Coast fever by the infection and treatment method]Cost analysis of immunization of East Coast fever by the infection and treatment method

East Coast fever is an acute, leukemia-like disease of cattle and Cape buffalo that is endemic in eastern, central, and southern Africa, where the disease causes high mortality and losses in livestock production. It is caused by the parasite Theileria parva, which infects bovine lymphocytolysis....


Ole-MoiYoi, O.K.[Casein kinase in theileriosis]Casein kinase in theileriosis
Toye, Philip G.Teale, A.J.[Gene transfection in mammalian cells and its application in studies of immunity to East Coast fever]Gene transfection in mammalian cells and its application in studies of immunity to East Coast fever
Goddeeris, B.M.Katende, J.M.Irvin, A.D.Chumo, R.S.C.[Indirect fluorescent antibody test for experimental and epizootiological studies on East Coast fever (Theileria parva infection in cattle): Evaluation of a cell culture schizont antigen fixed and stored in suspension]Indirect fluorescent antibody test for experimental and epizootiological studies on East Coast fever (Theileria parva infection in cattle): Evaluation of a cell culture schizont antigen fixed and stored in suspension
Shitakha, V.M.Nantulya, V.M.Musoke, A.J.Ramasamy, R.Buscher, G.[Complement activation and fibrinolysis during infection with Theileria parva (East Coast fever) in cattle]Complement activation and fibrinolysis during infection with Theileria parva (East Coast fever) in cattle

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