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Kornblatt, M.J.Mpimbaza, G.W.N.Lonsdale-Eccles, J.D.[Characterization of an endopeptidase of Trypanosoma brucei brucei]Characterization of an endopeptidase of Trypanosoma brucei brucei

A two species comparative genome scanning approach has been taken to mapping, and eventually identifying, genes at quantitative trait loci (QTL) influencing resistance to trypanosomosis due to infection with Trypanosoma congolense. Using two large murine F2 and two F6 advanced intercross populati...


Teale, A.J.Agaba, MorrisClapcott, S.J.Gelhaus, A.Haley, C.Psifidis, A.Horstmann, R.Iraqui, F.Kemp, Stephen J.Nilsson, P.Schwerin, M.Sekikawa, K.Soller, M.Sugimoto, Y.Womack, J.[Resistance to trypanosomosis: Of markers, genes and mechanisms]Resistance to trypanosomosis: Of markers, genes and mechanisms

This paper addresses issues surrounding measurment of the potential productivity gains from new livestock technologies and the returns to international livestock research. The approach, applicable to many livestock production constraints and technologies, uses geographic information systems (GIS)...


Kristjanson, Patricia M.Swallow, B.M.Rowlands, G.J.Kruska, R.L.Leeuw, P.N. de[Measuring the costs of African animal trypanosomosis, the potential benefits of control and returns to research]Measuring the costs of African animal trypanosomosis, the potential benefits of control and returns to research

The aim of this study was to assess, whether polymerase chain reaction (PCR) allows sensitive screening of treatment failure suspicions in areas, where drug resistance against African animal trypanosomosis (AAT) appears to be a problem. PCR was used to detect trypanosome infections prior to, 14 ...


Gall, Y.Woitag, T.Bauer, B.Sidibe, I.McDermott, John J.Mehlitz, D.Clausen, P.H.[Trypanocidal failure suggested by PCR results in cattle field samples]Trypanocidal failure suggested by PCR results in cattle field samples

The variable antigen type (VAT) RoTat 1.2 has been cloned from a T. evansi strain, isolated in 1982 from a water buffalo in Indonesia. All T. evansi isolates hitherto tested express this VAT. In a study on the differential diagnosis of T. equiperdum and T. evansi in horses, we investigated serolo...


Claes, F.Verloo, D.Waal, D.T. deUrakawa, T.Majiwa, P.A.O.Goddeeris, B.M.Buscher, P.[Expression of RoTat 1.2 cross-reactive variable antigen type in Trypanosoma evansi and T. equiperdum]Expression of RoTat 1.2 cross-reactive variable antigen type in Trypanosoma evansi and T. equiperdum

It is increasingly common to combine Microarray and Quantitative Trait Loci data to aid the search for candidate genes responsible for phenotypic variation. Workflows provide a means of systematically processing these large datasets and also represent a framework for the re-use and the explicit d...


Fisher, P.Hedeler, C.Wolstencroft, K.Hulme, H.Noyes, H.Kemp, Stephen J.Stevens, R.Brass, A.[A systematic strategy for large-scale analysis of genotype-phenotype correlations: identification of candidate genes involved in African trypanosomiasis]A systematic strategy for large-scale analysis of genotype-phenotype correlations: identification of candidate genes involved in African trypanosomiasis
Matemba, L.E.Fèvre, Eric M.Kibona, S.N.Picozzi, K.Cleaveland, S.Shaw, A.P.[Quantifying the burden of rhodesiense sleeping sickness in Urambo District, Tanzania]Quantifying the burden of rhodesiense sleeping sickness in Urambo District, Tanzania
Bronsvoort, B.M. de C.Wissmann, B. vonFèvre, Eric M.Handel, I.G.Picozzi, K.Welburn, S.C.[No gold standard estimation of the sensitivity and specificity of two molecular diagnostic protocols for Trypanosoma brucei spp. in Western Kenya]No gold standard estimation of the sensitivity and specificity of two molecular diagnostic protocols for Trypanosoma brucei spp. in Western Kenya

A one-year longitudinal study was conducted in 92 smallholder diary farms in Kwale district of Kenya, to evaluate the efficacy of Spot-on® (a 10% deltamethrin pour-on) in the control of East Coast fever, anaplasmosis, babesiosis and trypanosomosis. A comparison of the annual incidence and mortali...


Muraguri, G.R.McLeod, A.McDermott, John J.[Efficacy of a deltamethrin-based pour-on in the control of tick-borne diseases and trypanosomosis in Kwale District, Kenya]Efficacy of a deltamethrin-based pour-on in the control of tick-borne diseases and trypanosomosis in Kwale District, Kenya

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