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African trypanosomes infect cattle and humans in tsetse fly-infested areas of sub-Saharan Africa, causing sleeping sickness in humans and nagana in livestock. To date, no vaccines are available to combat these economically important diseases. In order to develop safe and protective vaccines, the ...

The advances in genomics technologies and genome analysis methods that offer new leads for accelerating discovery of putative targets for developing overall control tools are reviewed in Chapter 1. In Chapter 2, a PCR typing method based on restriction fragment length polymorphism analysis of the...

This collection of papers (submitted as a doctoral thesis) considers the various aspects of cellular differentiation and genetics of the trypanosome life cycle. The first chapters gives a general introduction to African trypanosomiasis. The next 4 discuss the DNA content of the genus Trypanosoma,...

The history of theileriosis in Zimbabwe is presented covering the period from the introduction of East Coast Fever in 1901 to the mid-1980s. This is followed by a series of 8 papers on the following topics: occurrence, isolation and characterization, epidemiology, age resistance, transmission by ...

Lack of effective tick and tick-borne disease (TBD) control is among the factors limiting dairy production in Uasin Gishu District in Kenya. Besides constraining productivity through morbidity, TBDs are among the most important causes of cattle deaths, most serious being East Coast fever (ECF). I...

Theileria are tick-transmitted, haemoprotozoan parasites infecting wild and domestic ungulates throughout many areas of the world. The most economically important parasite of sheep and goats in many parts of Asia is T. lestoquardi (syn. T. hirci) which causes the disease known as malignant ovine/...