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World Health Organization. Advisory Committee on Health Research[Genomics and world health: report of the Advisory Committee on Health Research]

Background: The clawed African frog Xenopus laevis has been one of the main vertebrate models for studies in developmental biology. However, for genetic studies, Xenopus tropicalis has been the experimental model of choice because it shorter life cycle and due to a more tractable genome that does...


Riadi, G.Ossandón, F.Larraín, J.Melo, F.[Towards the bridging of molecular genetics data across Xenopus species]Towards the bridging of molecular genetics data across Xenopus species

المجلس التنفيذي, 112[علم المجينيات والصحة العالمية: تقرير اللجنة الاستشارية المعنية بالبحوث الصحية: تقرير من المديرة العامة]

The manifestation of mitochondrial DNA (mtDNA) diseases depends on the frequency of heteroplasmy (the presence of several alleles in an individual), yet its transmission across generations cannot be readily predicted owing to a lack of data on the size of the mtDNA bottleneck during oogenesis. Fo...


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