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Nandam, D.Daubenberger, C.A.Mpimbaza, G.W.N.Pearson, T.W.[A rapid, single step purification method for immunogenic members of the hsp 70 family. Validation and application]A rapid, single step purification method for immunogenic members of the hsp 70 family. Validation and application
McElwain, T.F.Perryman, L.E.Musoke, A.J.McGuire, T.C.[Molecular characterization and immunogenicity of neutralization-sensitive Babesia bigemina merozoite surface proteins]Molecular characterization and immunogenicity of neutralization-sensitive Babesia bigemina merozoite surface proteins
Kachani, M.Spooner, R.L.[Anti-lymphocyte antibodies generated in animals immunised wtih Theileria annulata infected cells]Anti-lymphocyte antibodies generated in animals immunised wtih Theileria annulata infected cells
Nantulya, V.M.Doua, F.Molisho, S.[Diagnosis of Trypanosoma brucei gambiense sleeping sickness using an antigen detection enzyme-linked immunosorbent assay]Diagnosis of Trypanosoma brucei gambiense sleeping sickness using an antigen detection enzyme-linked immunosorbent assay

A monoclonal antibody (MAb)Tv27 employed in an antigen-detection enzyme immunosorbent assay (Ag-ELISA) for diagnosis of Trypanosoma vivax infection was shown to react with a T. vivax-specific protein of an approximate molecular weight of 10 kDa. This protein is diffusely distributed throughout th...


Masake, R.A.Ole-MoiYoi, O.K.Urakawa, T.Hirumi, H.Majiwa, P.A.O.Wells, C.W.Minja, S.H.Makau, J.M.Nantulya, V.M.[Immunological characterization and expression in Escherichia coli and Baculovirus systems of a Trypanosoma vivax antigen detected in the blood of infected animals]Immunological characterization and expression in Escherichia coli and Baculovirus systems of a Trypanosoma vivax antigen detected in the blood of infected animals

After analysis of flowcytometry data on bovine and ovine cells and immunoprecipitation studies, a cluster of seven MAbs-CAPP2 (3W-232), IL-A164 (M430), IL-A166 (3W-226), IVA30 (3W-069), IVA31 (3W-468), IVA38 (3W-349) and IVA125 (3W 528) - was shown to detect bovine and ovine CD41/Cd61 (also known...


Mateo, A.Pintado, C.O.Lastra, J.de laDusinsky, R.Simon, M.Naessens, JanLlanes, D.[Ruminant cluster CD41/CD61]Ruminant cluster CD41/CD61
Murray, M.Morrison, W. Ivan[Non-specific induction of increased resistance in mice to Trypanosoma congolense and Trypanosoma brucei brucei by immunostimulants]Non-specific induction of increased resistance in mice to Trypanosoma congolense and Trypanosoma brucei brucei by immunostimulants

T cell responses contribute to immunity against many intracellular infections. There is, for example, strong evidence that major histocompatibility complex (MHC) class I-restricted cytotoxic T lymphocytes (CTLs) play an essential role in mediating immunity to East Coast fever (ECF), a fatal lymph...


Nene, VishvanathSvitek, NicholasToye, Philip G.Golde, W.T.Barlow, J.Buus, SorenNielsen, Morten[Designing bovine T cell vaccines via reverse immunology]Designing bovine T cell vaccines via reverse immunology

The protozoan parasite Theileria parva causes a usually fatal disease in cattle, known as East Coast fever. Cattle can be vaccinated by injecting live parasites simultaneously with long acting oxytetracycline (the Infection and Treatment Method, ITM). The immunity induced by ITM is believed to be...


Steinaa, LucillaSaya, R.Awino, EliasToye, Philip G.[Cytotoxic T lymphocytes from cattle immunized against Theileria parva exhibit pronounced cross-reactivity among different strain-specific epitopes of the Tp1 antigen]Cytotoxic T lymphocytes from cattle immunized against Theileria parva exhibit pronounced cross-reactivity among different strain-specific epitopes of the Tp1 antigen

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