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To map the genetic sources of trypanotolerance in mice, a linkage analysis of survival following trypanosome challenge was performed by selective genotyping in a large F2 population produced by crossing the resistant C57BL/6 and susceptible BALB/c inbred mouse lines. We report evidence of a chrom...


Kemp, Stephen J.Darvasi, A.Soller, M.Teale, A.J.[Genetic control of resistance to trypanosomiasis]Genetic control of resistance to trypanosomiasis

Murine models have suggested that CD8 T cells might play a major parasite-promoting role in African trypanosomiasis. To assess the role of these cells in a natural host environment, we have depleted CD8 cells from Boran cattle in vivo and subsequently infected these animals with Trypanosoma congo...


Sileghem, M.R.Naessens, Jan[Are CD8 T cells involved in control of African trypanosomiasis in a natural host environment?]Are CD8 T cells involved in control of African trypanosomiasis in a natural host environment?

A bioassay was used to measure erythropoietin (EPO) concentrations in calves with haemorrhagic anaemia due to blood loss and in calves with anaemia due to Trypanosoma congolense infection. The bioactivity of EPO was measured in the assay by its stimulatory effect on 125I-deoxyuridine incorporatio...


Buza, J.J.Logan-Henfrey, L.L.Andrianarivo, A.G.Williams, D.J.L.[Rise in erythropoietin concentrations in experimental Trypanosoma congolense infection of calves]Rise in erythropoietin concentrations in experimental Trypanosoma congolense infection of calves

Nuclear extrachromosomal DNA elements have been identified in several kinetoplastids such as Leishmania and Trypanosoma cruzi, but never in Trypanosoma brucei. They can occur naturally or arise spontaneously as the result of sublethal drug exposure of parasites. In most cases, they are represente...


Alsford, N.S.Navarro, M.Jamnadass, Ramni H.Dunbar, H.Ackroyd, M.Murphy, N.B.Gull, K.Ersfeld, K.[The identification of circular extrachromosomal DNA in the nuclear genome of Trypanosoma brucei]The identification of circular extrachromosomal DNA in the nuclear genome of Trypanosoma brucei
Hutchinson, O.C.Fèvre, Eric M.Carrington, M.Welburn, S.C.[Lessons learned from the emergence of a new Trypanosoma brucei rhodesiense sleeping sickness focus in Uganda]Lessons learned from the emergence of a new Trypanosoma brucei rhodesiense sleeping sickness focus in Uganda

A project implemented from 2003 to 2005 trained women in Chitwan District, Nepal, in hygienic dairy production using a process of social mobilization. The aim of this research was to assess if the prevalence of mastitis in water buffalo in the households of women who were trained was lower one ye...


Ng, L.Jost, ChristineRobyn, M.Dhakal, I.P.Bett, Bernard K.Dhakal, P.Khadka, R.[Impact of livestock hygiene education programs on mastitis in smallholder water buffalo (Bubalus bubalis) in Chitwan, Nepal]Impact of livestock hygiene education programs on mastitis in smallholder water buffalo (Bubalus bubalis) in Chitwan, Nepal
Fèvre, Eric M.Coleman, P.G.Odiit, M.Magona, J.W.Welburn, S.C.Woolhouse, Mark E.J.[The origins of a new Trypanosoma brucei rhodesiense sleeping sickness outbreak in eastern Uganda]The origins of a new Trypanosoma brucei rhodesiense sleeping sickness outbreak in eastern Uganda
Autor: Francis, P.A.

Relates livestock management systems to characteristic problems facing small ruminant producers in the physical and economic environment of four states of southeast Nigeria, viz, Bendel Anambra, Imo and Rivers states. Assesses the implications of increasing population density and intensified agri...


Francis, P.A.[Some aspects of sheep and goat management in southeast Nigeria]Some aspects of sheep and goat management in southeast Nigeria

Most studies of infectious diseases in East African cattle have concentrated on gastro-intestinal parasites and vector-borne diseases. As a result, relatively little is known about viral diseases, except for those that are clinically symptomatic or which affect international trade such as foot an...


Callaby, R.Toye, Philip G.Jennings, A.Thumbi, S.M.Wyk, I.C. vanHanotte, Olivier H.Mbole-Kariuki, Mary N.Bronsvoort, B.M. de C.Kruuk, L.E.B.Woolhouse, Mark E.J.Kiara, Henry K.[Seroprevalence of respiratory viral pathogens of indigenous calves in western Kenya]Seroprevalence of respiratory viral pathogens of indigenous calves in western Kenya

Most emerging diseases of humans originate in animals, and zoonotic emerging infectious diseases (EIDs) threaten human, animal, and environment health. We report on a scoping study to assess actors, linkages, priorities, and needs related to management of these diseases from the perspective of ke...


Grace, DeliaGilbert, J.Lapar, Ma. LucilaUnger, FredFèvre, Eric M.Hung Nguyen-VietSchelling, E.[Zoonotic emerging infectious disease in selected countries in Southeast Asia: Insights from ecohealth]Zoonotic emerging infectious disease in selected countries in Southeast Asia: Insights from ecohealth

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