Descubre y comparte nuestro conocimiento público

Introducción: La salud se ve la favorecida de una manera muy especial por el extraordinario desarrollo de la tecnología. Desarrollo: En la presente reflexión se pretende, en primer lugar, definir lo que se entiende por tecnología, para luego dilucidar su rol actual en el área de la salud. A travé...

Neurodevelopmental disorders offer insight into synaptic mechanisms. To unbiasedly uncover these mechanisms, we studied the 22q11.2 syndrome, a recurrent copy number variant, which is the highest schizophrenia genetic risk factor. We quantified the proteomes of 22q11.2 mutant human fibroblasts fr...

Background: Genetically engineered mice (GEM) are essential tools for understanding gene function and disease modeling. Historically, gene targeting was first done in embryonic stem cells (ESCs) derived from the 129 family of inbred strains, leading to a mixed background or congenic mice when cro...

Background: Chromosome 22q11.2 microdeletion syndrome, a disorder caused by heterozygous loss of genetic material in chromosome region 22q11.2, has a broad range of clinical symptoms. The most common congenital anomalies involve the palate in 80% of patients, and the heart in 50–60% of them. The ...

Ocean acidification (OA) is one of the largest emerging and significant environmental threats for the aquaculture industry, jeopardizing its role as an alternative for supporting food security. Moreover, market conditions, characterized by price volatility and low value-added products, could exac...

Ocean Acidifcation (OA) has become one of the most studied global stressors in marine science during the last ffteen years. Despite the variety of studies on the biological efects of OA with marine commercial species, estimations of these impacts over consumers’ preferences have not been studied ...

This paper presents a joint estimation of the willingness to pay for conservation activities aimed at preserving the flow of ecosystem services provided by a marine protected area network and respondents’ personal discount rate using a contingent valuation survey. This work contributes to the lit...

Evidence from south-central Chile shows that the concentration limits for PM10 and PM2.5, defined by both the World Health Organization and national standards, are systematically exceeded, affecting approximately 10 million people. Among the sources of this pollution, firewood use accounts for th...

The last decade has seen a significant global increase in immigration. This large growth has caused an increasing opposition to immigration in local populations in many parts of the world, partly because of a commonly held belief that immigration increases crime. Using data from Chile, spanning 1...