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Human immunodeficiency virus type 1 (HIV-1) and type 2 (HIV-2) gene expression. HIV-1 and HIV-2 are the etiological agents of AIDS in humans. They have developed sophisticated strategies to drive the expression of a complex genome that codes for several p

Based on our preliminary data describing the effect of maternal hypothyroxinemia on the CNS and the role of CD3ζ in neuronal connectivity, we propose the following hypothesis: “CD3ζ expression and function is altered in neurons from the progeny gestated i

Alzheimer’s disease (AD) is an age-related, neurodegenerative disease that results in memory loss, behavior and personality changes, as well as a decrease in thinking abilities. Among tissue manifestations is included the generation of amyloid plaques into the extracellular brain parenchyma compo...

El canal de potasio rectificador de entrada Kir7.1 se expresa en el nefrón y su rol es actualmente especulativo. Nuestros estudios preliminares en riñón de ratón muestran que Kir7.1 se localiza principalmente en la membrana apical de la rama gruesa ascendente de Henle (TAL). Postulamos que Kir7.1...

Processing of information in the brain is metabolically expensive. The brain represents only 2% of our body mass, but consumes 20% of its oxygen and glucose. Glucose, transported by the blood, is the major source of energy used by the brain for neuronal activity. Astrocytes provide by their periv...

This collaboration between a group of Chilean and French researchers is circumscribed in the frame of scientific problems imposed by the environmental constraints in conception and management of the supply chains. This topic is very extensive, so there is a huge quantity of works in tihis area. A...