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INTRODUCTION Gastrointestinal stromal tumors (GIST) are the most frequent mesenchymal tumors of the digestive tract. Extraintestinal locations (EGIST) have been described showing similar pattern of immunohistochemical markers than GIST. Inhibitors of tyrosine kinases such as Imatinib or Sunitinib...


Quezada, N.Acevedo, F.Marambio, A.León, F.Galindo, H.Roa, J. C.Jarufe, N.[Complete pathological response to Imatinib mesylate in an extraintestinal gastrointestinal stromal tumor]Complete pathological response to Imatinib mesylate in an extraintestinal gastrointestinal stromal tumor

Introduction: Recent reports show that pregnancy-associated breast cancer (PABC) survival is similar to that of non-pregnant young patients. We evaluate the characteristics and prognosis of PABC patients treated in our cancer centre. Patients and methods: We identified patients with invasive PAB...


Sánchez, C.Acevedo, F.Medina, L.Ibáñez, C.Razmilic, D.Navarro, M. E.Camus, M.[Breast cancer and pregnancy: A comparative analysis of a Chilean cohort]Breast cancer and pregnancy: A comparative analysis of a Chilean cohort

Interstitial lung disease (ILD) is rare and encompasses a heterogeneous group of diseases, and is even rarer in children than in adults. ILDs compromise more than 100 different entities, including pulmonary alveolar proteinosis (PAP). There are many causes of PAP in children, including surfactant...


Strickler, A.Boza, M. L.Koppmann, A.Gonzalez, S.[Autoimmune pulmonary proteinosis in a Chilean teenager, a rare aetiology of interstitial lung disease]Autoimmune pulmonary proteinosis in a Chilean teenager, a rare aetiology of interstitial lung disease

Diverse hypotheses have been proposed with the aim to explain the extinction of Late Pleistocene/Holocene mammals, including the Megafauna from America. Some authors support that human being was the direct responsible of extinction by means of intensive hunting, as proposed by the 'blitzkrieg' or...


Pérez, AlbertoAgnolin, Federico L.[Were human-introduced diseases the responsible for Pleistocene-Holocene megafaunal extinctions? First evidence from South America]Were human-introduced diseases the responsible for Pleistocene-Holocene megafaunal extinctions? First evidence from South America
Montserrat Guerra, MariaHenzi, RobertoOrtloff Trautmann, AlexanderLichtin, NicoleVio, KarinJimenez, Antonio J.Dolores Dominguez Pinos, MariaGonzalez, CesarClara Jara, MariaHinostroza, FernandoRodriguez, SaraJara, MaryorisOrtega, EduardoGuerra, FranciscoSival, Deborah A.den Dunnen, Wilfred F. A.Perez Figares, Jose M.McAllister, James P.Johanson, Conrad E.Rodriguez, Esteban M.[Cell Junction Pathology of Neural Stem Cells Is Associated With Ventricular Zone Disruption, Hydrocephalus, and Abnormal Neurogenesis]Cell Junction Pathology of Neural Stem Cells Is Associated With Ventricular Zone Disruption, Hydrocephalus, and Abnormal Neurogenesis

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