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Over the past few years, research at ILRI and by its partners has identified genomic regions controlling trypanotolerance in cattle and in mice. In mice many of the genes lying within these genomic regions have been identified, leading the way to identification of the genes controlling trypanotol...


Gibson, John P.[Towards an understanding of genetic control of trypanotolerance]Towards an understanding of genetic control of trypanotolerance
Moloo, S.K.[Studies on the transmission of a West African stock of Trypanosoma vivax to rabbits, rats, mice and goats by Glossina morsitans morsitans and G. m. centralis]Studies on the transmission of a West African stock of Trypanosoma vivax to rabbits, rats, mice and goats by Glossina morsitans morsitans and G. m. centralis

In the present study, we used newly developed F11 generation mouse advanced intercross lines (AIL) to fine map Pas1–3 quantitative trait loci (QTL). The (A/J x C57BL/6) F11 AIL mouse population was created by crossing lung tumor-resistant C57BL/6 mice with lung tumor-susceptible A/J mice. By se...


Wang, M.Lemon, W.J.Liu, G.Wang, Y.Iraqi, F.A.Malkinson, A.M.You, M.[Fine mapping and identification of candidate pulmonary adenoma susceptibility 1 genes using advanced intercross lines]Fine mapping and identification of candidate pulmonary adenoma susceptibility 1 genes using advanced intercross lines
Autor: Iraqi, F.A.

High-resolution mapping of quantitative trait loci (QTLs) is an essential step towards positional cloning and identification of the corresponding genes. Most QTL detection and mapping studies in mice have been carried out using F2 intercross and backcross populations. As a consequence of the limi...


Iraqi, F.A.[Fine mapping of quantitative trait loci using advanced intercross lines of mice and positional cloning of the corresponding genes]Fine mapping of quantitative trait loci using advanced intercross lines of mice and positional cloning of the corresponding genes
Pearson, T.W.Roelants, G.E.Pinder, M.Lundin, L.B.Mayor-Withey, K.S.[Immune depression in trypanosome-infected mice. 3. Suppressor cell]Immune depression in trypanosome-infected mice. 3. Suppressor cell
Gee, A.L.W. deShah, S.D.Doyle, J.J.[Trypanosoma vivax. Sequence of antigenic variants in mice and goats]Trypanosoma vivax. Sequence of antigenic variants in mice and goats
Mahan, S.M.Hendershot, L.Black, S.J.[Control of trypanodestructive antibody responses and parasitemia in mice infected with Trypanosoma (Duttonella) vivax]Control of trypanodestructive antibody responses and parasitemia in mice infected with Trypanosoma (Duttonella) vivax

Four Trypanosoma (T.) congolense reference clones with known isometamidium sensitivity and 16 T. congolense stocks from cattle in Kenedougou in south-western Burkina Faso, an area with known history of drug resistance, were characterised with the standard mouse test (SMT) and the drug incubatio...


Knoppe, T.N.Bauer, B.McDermott, John J.Peregrine, A.S.Mehlitz, D.Clausen, P.H.[Isometamidium sensitivity of Trypanosoma congolense stocks from cattle in West Africa tested in mice and the drug incubation infectivity test]Isometamidium sensitivity of Trypanosoma congolense stocks from cattle in West Africa tested in mice and the drug incubation infectivity test

Quantitative trait loci (QTL) associated with resistance to an intestinal worm in a well-defined murine model are described. These have been identified in an F(2) population derived from resistant (SWR) and susceptible (CBA) parental mouse strains infected with the gastro-intestinal nematode par...


Iraqi, F.A.Behnke, J.M.Menge, D.M.Lowe, A.M.Teale, A.J.Gibson, John P.Baker, L.R.Wakelin, D.R.[Chromosomal regions controlling resistance to gastro-intestinal nematode infections in mice]Chromosomal regions controlling resistance to gastro-intestinal nematode infections in mice

We developed an F(11) AIL population from an F(1) cross of A/J (susceptible) and C57BL/6J (resistant) mouse strains. One thousand F(11) mice were challenged with P.c. chabaudi 54X, and 340 mice selected from the phenotypic extremes for susceptibility and resistance were genotyped for microsatel...


Hernández Valladares, M.Naessens, JanGibson, John P.Musoke, A.J.Nagda, S.M.Rihet, P.Ole-MoiYoi, O.K.Iraqi, F.A.[Confirmation and dissection of QTL controlling resistance to malaria in mice]Confirmation and dissection of QTL controlling resistance to malaria in mice

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