Trypanosomes are covered with a dense layer of antigenically identical glycoproteins. These molecules are highly immunogenic and elicit an antibody response in the infected host. Antibodies against the surface-exposed epitopes of the trypanosome variable surface glycoproteins (VSG) mediate the de...
Williams, D.J.L.
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Taylor, K.
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Wilkie, B.
,
Gichuki, B.
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Authié, E.
,
[Antibody responses to the surface-exposed epitopes of the trypanosome variable surface glycoprotein in N'Dama and Boran cattle]
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Antibody responses to the surface-exposed epitopes of the trypanosome variable surface glycoprotein in N'Dama and Boran cattle
Reports the viability, reproduction and associated growth rates achieved by grade Boran cattle maintained by chemoprophylaxis at Mkwaja Ranch in Tanzania, over the ten years, from 1973 to 1983.
Jibbo, J.M.C.
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Durkin, J.W.
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Light, D.
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Murray, M.
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Sones, Keith R.
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Trail, J.C.M.
,
[Chemoprophylaxis: Its successful use in the control of trypanosomiasis in Boran cattle, at Mkwaja ranch, Tanzania]
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Chemoprophylaxis: Its successful use in the control of trypanosomiasis in Boran cattle, at Mkwaja ranch, Tanzania
The prevalence, species and intensity of trypanosome parasitaemia in different livestock species, breeds, age groups and management systems are reported from Togo for trypanosotolerant sheep and goats in the Sokode area. The effects of these trypanosome parasitaemias on health and production trai...
Defly, A.
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Awuome, K.
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Bokovi, K.
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D'Ieteren, G.D.M.
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Grundler, G.
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Handlos, Michael
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Itty, P.
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Leak, S.G.A.
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Maehl, J.H.H.
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Mawuena, K.
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Morkramer, G.
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Nagda, S.M.
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Paling, R.W.
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Rarieya, J.M.
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Thorpe, W.R.
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Trail, J.C.M.
,
[Effect of trypanosome infection on livestock health and production in Togo]
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Effect of trypanosome infection on livestock health and production in Togo
Peregrine, A.S.
,
[Factors influencing the duration of isometamidium prophylaxis against bovine trypanosomiasis.]
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Factors influencing the duration of isometamidium prophylaxis against bovine trypanosomiasis.
The International Laboratory for Research on Animal Diseases (ILRAD) has recently developed interests in several areas of cell biology and biochemistry that are relevant to trypanosomiasis and theileriosis (East Coast Fever (ECF)). The reasons for this interest stem from a perceived difficulty of...
Lonsdale-Eccles, J.C.
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Lenahan, J.K.
,
[Protein traffic in parasites and mammalian cells. Proceedings of a workshop]
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Protein traffic in parasites and mammalian cells. Proceedings of a workshop
West African N'Dama cattle have developed a genetic capacity to survive, reproduce and remain productive under trypanosomosis risk. The cellular and molecular bases of this so-called trypanotolerance are not known, but the trait is manifested by the N'Dama's greater capacity to control parasitae...
Naessens, Jan
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Leak, S.G.A.
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Kennedy, D.J.
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Kemp, Stephen J.
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Teale, A.J.
,
[Responses of bovine chimaeras combining trypanosomosis resistant and susceptible genotypes to experimental infection with Trypanosoma congolense]
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Responses of bovine chimaeras combining trypanosomosis resistant and susceptible genotypes to experimental infection with Trypanosoma congolense
The first visible response in livestock to the bite of a trypanosome-infected tsetse fly is the formation of a localized skin reaction, also known as a chancre. This is an inflammatory response in the skin associated with swelling and an influx of cells. It is thought to be associated with an a...
Naessens, Jan
,
Mwangi, D.M.
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Buza, J.
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Moloo, S.K.
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[Local skin reaction (chancre) induced following inoculation of metacyclic trypanosomes in cattle by tsetse flies is dependent on CD4 T lymphocytes]
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Local skin reaction (chancre) induced following inoculation of metacyclic trypanosomes in cattle by tsetse flies is dependent on CD4 T lymphocytes
Development of anaemia in inflammatory diseases is cytokine-mediated. Specifically, the levels of tumour necrosis factor-α (TNF-α), produced by activated macrophages, are correlated with severity of disease and anaemia in infections and chronic disease. In African trypanosomiasis, anaemia develop...
Naessens, Jan
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Kitani, H.
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Nakamura, Y.
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Yagi, Y.
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Sekikawa, K.
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Iraqi, F.A.
,
[TNF-a mediates the development of anaemia in a murine Trypanosoma brucei rhodesiense infection, but not the anaemia associated with a murine Trypanosoma congolense infection]
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TNF-a mediates the development of anaemia in a murine Trypanosoma brucei rhodesiense infection, but not the anaemia associated with a murine Trypanosoma congolense infection
Development of anaemia in inflammatory diseases is cytokine-mediated. Specifically, the levels of tumour necrosis factor-alpha (TNF-alpha), produced by activated macrophages, are correlated with severity of disease and anaemia in infections and chronic disease. In African trypanosomiasis, anaemia...
Naessens, Jan
,
Kitani, H.
,
Nakamura, Y.
,
Yagi, Y.
,
Sekikawa, K.
,
Iraqi, F.A.
,
[TNF-alpha mediates the development of anaemia in a murine Trypanosoma brucei rhodesiense infection, but not the anaemia associated with a murine Trypanosoma congolense infection]
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TNF-alpha mediates the development of anaemia in a murine Trypanosoma brucei rhodesiense infection, but not the anaemia associated with a murine Trypanosoma congolense infection
Natural resistance to African trypanosomiasis in certain Bos taurus cattle in West Africa, called trypanotolerance, may hold solutions for control of this economically crippling disease. Comparison of immune responses between trypanotolerant and trypanosusceptible cattle have shown some differen...
Naessens, Jan
,
Teale, A.J.
,
Sileghem, M.R.
,
[Identification of mechanisms of natural resistance to African trypanosomiasis in cattle]
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Identification of mechanisms of natural resistance to African trypanosomiasis in cattle