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Examines the genetic basis of trypanotolerance with particular reference to Africa, environmental factors which can influence its stability like age, stress (work, pregnancy etc.), nutrition and disease, and the possible mechanisms responsible; looks at the tyrpanotolerance of different breeds.


Murray, M.Trail, J.C.M.[Genetic resistance to animal trypanosomiasis in Africa]Genetic resistance to animal trypanosomiasis in Africa

This review of the prospects for developing an immunization procedure against trypanosomiasis explores a number of promising avenues of research. Part I covers variable antigen types (VATs); metacyclic antigens; in vivo and in vitro attenuation; and molecular and genetic engineering. Part II, to ...


Murray, M.Barry, J.D.Morrison, W. IvanWilliams, R.O.Hirumi, H.Rovis, L.A.[A review of the prospects for vaccination in African trypanosomiasis. Part I]A review of the prospects for vaccination in African trypanosomiasis. Part I

Summarises the impact of trypanosomiasis on development of trypanotolerant livestock. Describes current genetic research being carried out by collaborating national and international organisations in the African Trypanotolerant Livestock Network, and discusses the importance of conserving these g...


Trail, J.C.M.D'Ieteren, G.D.M.Teale, A.J.[Trypanotolerance and the value of conserving livestock genetic resources]Trypanotolerance and the value of conserving livestock genetic resources
Moloo, S.K.[Interacting factors in the epidemiology of trypanosomiasis in an endemic/enzootic region of Uganda and its contiguous area of Kenya]Interacting factors in the epidemiology of trypanosomiasis in an endemic/enzootic region of Uganda and its contiguous area of Kenya

The review discusses the current field status of human and bovine trypanosomiases, and focuses on the molecular basis of innate and acquired control of African trypanosomes in people, cattle and Cape buffalo


Black, S.J.Seed, J.R.Murphy, N.B.[Innate and acquired resistance to African trypanosomiasis]Innate and acquired resistance to African trypanosomiasis

A household survey was conducted in six villages of Busia District, Kenya, to assess people's willingness to contribute labor and money to control the tsetse flies that transmit trypanosomiasis. A Heckman's two-step model was estimated to identify factors affecting the probability that a responde...


Echessah, P.N.Swallow, B.M.Kamara, D.W.Curry, J.J.[Willingness to contribute labor and money to tsetse control: application of contingent valuation in Busia District, Kenya]Willingness to contribute labor and money to tsetse control: application of contingent valuation in Busia District, Kenya

A visually read dot-enzyme linked immunosorbent asay (dot-ELISA) developed for the detection of trypanosomes in tsetse flies (Glossina spp.) was evaluated in the laboratory and under field conditions. In the evaluation, the fly dissection method was used as a standard technique and compared to th...


Ouma, J.O.Masake, R.A.Masiga, Daniel K.Moloo, S.K.Njuguna, J.T.Ndung'u, J.M.[Comparative sensitivity of dot-ELISA, PCR and dissection method for the detection of trypanosome infections in tsetse flies (Diptera: Glossinidae)]Comparative sensitivity of dot-ELISA, PCR and dissection method for the detection of trypanosome infections in tsetse flies (Diptera: Glossinidae)

Cattle from 50 farms in Mukono County, Uganda, were monitored for trypanosomes every second month over an 18-month period (1995–1996) by mini-anion exchange chromatography and haematocrit centrifugation techniques. Eighteen trypanosome isolates collected from cattle during this period were charac...


Olila, D.McDermott, John J.Eisler, M.C.Mitema, E.S.Patzelt, R.J.Clausen, P.H.Poetzsch, C.J.Zessin, K.H.Mehlitz, D.Peregrine, A.S.[Drug sensitivity of trypanosome populations from cattle in a peri-urban dairy production system in Uganda]Drug sensitivity of trypanosome populations from cattle in a peri-urban dairy production system in Uganda

Sequential biopsies of sternal bone marrow (BM) of three trypanosusceptible Boran and three trypanotolerant N'Dama cattle were examined by light and transmission electron microscopy before and up to 112 days postinfection (DPI) with Trypanosoma congolense. Before infection, the percentage of cell...


Anosa, V.O.Logan-Henfrey, L.L.Wells, C.W.[The role of the bone marrow in bovine trypanotolerance. II. Macrophage function in Trypanosoma congolense - infected cattle]The role of the bone marrow in bovine trypanotolerance. II. Macrophage function in Trypanosoma congolense - infected cattle

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